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A5ZY13

- A5ZY13_9FIRM

UniProt

A5ZY13 - A5ZY13_9FIRM

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Protein
Submitted name: Glycosyl hydrolase, family 31
Gene
RUMOBE_03919
Organism
Ruminococcus obeum ATCC 29174
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei197 – 1971GlucoseImported
Binding sitei404 – 4041GlucoseImported
Binding sitei420 – 4201GlucoseImported
Binding sitei478 – 4781GlucoseImported

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase

Protein family/group databases

CAZyiGH31. Glycoside Hydrolase Family 31.

Names & Taxonomyi

Protein namesi
Submitted name:
Glycosyl hydrolase, family 31Imported (EC:3.2.1.-Imported)
Gene namesi
ORF Names:RUMOBE_03919Imported
OrganismiRuminococcus obeum ATCC 29174Imported
Taxonomic identifieri411459 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesLachnospiraceaeBlautia

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3M46X-ray2.66A/B1-663[»]
3M6DX-ray2.90A/B1-663[»]
3MKKX-ray1.91A/B1-663[»]
3N04X-ray2.02A/B1-663[»]
3NSXX-ray1.57A/B1-663[»]
3NUKX-ray2.06A/B1-663[»]
3PHAX-ray2.17A/B/C/D1-663[»]
3POCX-ray1.99A/B1-663[»]

Miscellaneous databases

EvolutionaryTraceiA5ZY13.

Family & Domainsi

Family and domain databases

InterProiIPR011013. Gal_mutarotase_SF_dom.
IPR000322. Glyco_hydro_31.
IPR025887. Glyco_hydro_31_N_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF13802. Gal_mutarotas_2. 1 hit.
PF01055. Glyco_hydro_31. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 2 hits.
SSF74650. SSF74650. 1 hit.
PROSITEiPS00129. GLYCOSYL_HYDROL_F31_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5ZY13-1 [UniParc]FASTAAdd to Basket

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MIRKYRYGAP FDTEALTEKI ETAEEAFPYG EISQKEGFAF TYIMDEDDIV    50
YGLGESNRGI NKRGYCYISN CTDDPIHTED KRSLYGAHNF IIVSGKTTFG 100
LFFDYPSKLT FDIGYTRMDT LKVSCENADL DIYVIEGENA YDIVKQFRRV 150
IGRSYIPPKF AFGFGQSRWG YTTKEDFRAV AKGYRENHIP IDMIYMDIDY 200
MQDFKDFTVN EKNFPDFPEF VKEMKDQELR LIPIIDAGVK VEKGYEVYEE 250
GVKNNYFCKR EDGSDFVAAV WPGDTHFPDM LNPEARKWFG DKYRFLIDQG 300
IEGFWNDMNE PAIFYSSEGL AEAKEFAGEF AKDTEGKIHP WAMQAKMKDI 350
VNSPEDYKRF YHNVNGKKIR HDKVHNLFGY NMTRAAGEAF ERIDPEKRFL 400
MFSRSSYIGM HRYGGIWMGD NKSWWSHILL NLKMLPSLNM CGFMYTGADL 450
GGFGDDTTRD LLLRFLALGV FTPLMRDHAA EGTREQECYQ FENIEDFRSV 500
INARYRLVPY LYSEYMKAAL NDDMYFKPLG FVYPDDKMAI RVEDQLMLGN 550
EIMIAPVYEQ NARGRYVYLP EEMKFIKFMP DGSISEEVLE KGVHYVDVAL 600
NEVPLFIRSG KCIPVAEAAE CVKDIDTENM QLIGYEGSSY TLYEDDGIHK 650
DYDKKENYRV LTK 663
Length:663
Mass (Da):77,083
Last modified:July 24, 2007 - v1
Checksum:i8FAA32F7735D97E8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAVO02000029 Genomic DNA. Translation: EDM85535.1.

Genome annotation databases

EnsemblBacteriaiEDM85535; EDM85535; RUMOBE_03919.
PATRICi29798544. VBIRumObe16879_1928.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAVO02000029 Genomic DNA. Translation: EDM85535.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3M46 X-ray 2.66 A/B 1-663 [» ]
3M6D X-ray 2.90 A/B 1-663 [» ]
3MKK X-ray 1.91 A/B 1-663 [» ]
3N04 X-ray 2.02 A/B 1-663 [» ]
3NSX X-ray 1.57 A/B 1-663 [» ]
3NUK X-ray 2.06 A/B 1-663 [» ]
3PHA X-ray 2.17 A/B/C/D 1-663 [» ]
3POC X-ray 1.99 A/B 1-663 [» ]
ModBasei Search...

Protein family/group databases

CAZyi GH31. Glycoside Hydrolase Family 31.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai EDM85535 ; EDM85535 ; RUMOBE_03919 .
PATRICi 29798544. VBIRumObe16879_1928.

Miscellaneous databases

EvolutionaryTracei A5ZY13.

Family and domain databases

InterProi IPR011013. Gal_mutarotase_SF_dom.
IPR000322. Glyco_hydro_31.
IPR025887. Glyco_hydro_31_N_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
Pfami PF13802. Gal_mutarotas_2. 1 hit.
PF01055. Glyco_hydro_31. 1 hit.
[Graphical view ]
SUPFAMi SSF51445. SSF51445. 2 hits.
SSF74650. SSF74650. 1 hit.
PROSITEi PS00129. GLYCOSYL_HYDROL_F31_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC 29174Imported.
  2. "Draft genome sequence of Ruminococcus obeum (ATCC 29174)."
    Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D., Gordon J.
    Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC 29174Imported.
  3. "Novel ?-glucosidase from human gut microbiome: substrate specificities and their switch."
    Tan K., Tesar C., Wilton R., Keigher L., Babnigg G., Joachimiak A.
    FASEB J. 24:3939-3949(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.91 ANGSTROMS) IN COMPLEX WITH GLUCOSE.
  4. "The crystal structure of the The crystal structure of the D420A mutant of the alpha-glucosidase (FAMILY 31) from Ruminococcus obeum ATCC 29174."
    Tan K., Tesar C., Wilton R., Keigher L., Babnigg G., Joachimiak A.
    Submitted (JUL-2010) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.57 ANGSTROMS).
  5. "THE CRYSTAL STRUCTURE OF THE W169Y mutant of ALPHA-GLUCOSIDASE (FAMILY 31) from RUMINOCOCCUS OBEUM ATCC 29174."
    Tan K., Tesar C., Wilton R., Keigher L., Babnigg G., Joachimiak A.
    Submitted (JUL-2010) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.06 ANGSTROMS).
  6. "The crystal structure of the D307A mutant of alpha-Glucosidase (FAMILY 31) from Ruminococcus obeum ATCC 29174 in complex with acarbose."
    Tan K., Tesar C., Wilton R., Keigher L., Babnigg G., Joachimiak A.
    Submitted (NOV-2010) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.99 ANGSTROMS).
  7. "The crystal structure of the W169Y mutant of alpha-glucosidase (gh31 family) from Ruminococcus obeum atcc 29174 in complex with acarbose."
    Tan K., Tesar C., Keigher L., Babnigg G., Joachimiak A.
    Submitted (NOV-2010) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.17 ANGSTROMS).

Entry informationi

Entry nameiA5ZY13_9FIRM
AccessioniPrimary (citable) accession number: A5ZY13
Entry historyi
Integrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: June 11, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3

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