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A5YMU1 (A5YMU1_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 1 RuleBase RU000369
EC=1.9.3.1 RuleBase RU000369
Gene names
Name:mt-Co1 MGI 102504
Synonyms:COXI EMBL ABQ81554.1
Encoded onMitochondrion EMBL ABQ81554.1
OrganismMus musculus (Mouse) EMBL ABQ81554.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length204 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B By similarity. RuleBase RU000369

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O. RuleBase RU000369

Pathway

Energy metabolism; oxidative phosphorylation. RuleBase RU000369

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity RuleBase RU000369.

Sequence similarities

Belongs to the heme-copper respiratory oxidase family. RuleBase RU000369

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL ABQ81554.1
Non-terminal residue2041 EMBL ABQ81554.1

Sequences

Sequence LengthMass (Da)Tools
A5YMU1 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 8FBA529A0265F839

FASTA20421,668
        10         20         30         40         50         60 
WAGMVGTALS ILIRAELGQP GALLGDDQIY NVIVTAHAFV MIFFMVMPMM IGGFGNWLVP 

        70         80         90        100        110        120 
LMIGAPDMAF PRMNNMSFWL LPPSFLLLLA SSMVEAGAGT GWTVYPPLAG NLAHAGASVD 

       130        140        150        160        170        180 
LTIFSLHLAG VSSILGAINF ITTIINMKPP AMTQYQTPLF VWSVLITAVL LLLSLPVLAA 

       190        200 
GITMLLTDRN LNTTFFDPAG GGDP

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References

[1]"The use of DNA barcoding for species identification of materials housed in a biorepository."
Lorenz J.G., Yancy H., Coppock D.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		EF568645 Genomic DNA. Translation: ABQ81554.1.
IPIIPI00355248.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA5YMU1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG102108.
InParanoidA5YMU1.

Enzyme and pathway databases

UniPathwayUPA00705.

Gene expression databases

ArrayExpressA5YMU1.
BgeeA5YMU1.
GenevestigatorA5YMU1.

Family and domain databases

Gene3D1.20.210.10. 1 hit.
InterProIPR000883. Cyt_c_Oxase_su1.
IPR023616. Cyt_c_Oxase_su1_dom.
[Graphical view]
PANTHERPTHR10422. PTHR10422. 1 hit.
PfamPF00115. COX1. 1 hit.
[Graphical view]
PRINTSPR01165. CYCOXIDASEI.
SUPFAMSSF81442. COX1. 1 hit.
PROSITEPS50855. COX1. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio35544846.

Entry information

Entry nameA5YMU1_MOUSE
AccessionPrimary (citable) accession number: A5YMU1
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: April 3, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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