false2007-07-102024-03-27124A5YBL8_HORSEHomozygosity mapping approach identifies a missense mutation in equine cyclophilin B (PPIB) associated with HERDA in the American Quarter Horse.Tryon R.C.White S.D.Bannasch D.L.doi:10.1016/j.ygeno.2007.03.0092007Genomics9093-102NUCLEOTIDE SEQUENCECrystal structures of wild-type and mutated cyclophilin B that causes hyperelastosis cutis in the American quarter horse.Boudko S.P.Ishikawa Y.Lerch T.F.Nix J.Chapman M.S.Bachinger H.P.doi:10.1186/1756-0500-5-6262012BMC Res. Notes5626X-RAY CRYSTALLOGRAPHY (1.10 ANGSTROMS) OF 34-216 IN COMPLEX WITH ZINC1.10A=34-2161.10A=34-216cyclophilin_ABH_likeCyclophilin-likeCyclophilin-like_dom_sfCyclophilin-type_PPIase_CSCyclophilin-type_PPIase_domPEPTIDYL-PROLYL CIS-TRANS ISOMERASEPEPTIDYL-PROLYL CIS-TRANS ISOMERASE HPro_isomeraseCSAPPISMRASECyclophilin-likeCSA_PPIASE_1CSA_PPIASE_2Peptidyl-prolyl cis-trans isomerasePPIase5.2.1.8PPIBPPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.Belongs to the cyclophilin-type PPIase family.PPIase cyclophilin-type4720454166122007-07-10123808e3aca40e351dea8ad555135535d9c90eMLRFSERNMKVLFAAALIVGSVFFLLLPGPSTADEKKKGPKVTVKVYFDLRIGDEDIGRVVIGLFGKTVPKTVDNFVALATGEKGFGYKDSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVETTKTDGRDKPLKDVTIADCGKIEVEKPFAIAKEtruetrue