A5XUQ6 (A5XUQ6_BURMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phospho-2-dehydro-3-deoxyheptonate aldolase PIRNR PIRNR001361
EC=2.5.1.54 PIRNR PIRNR001361

Alternative name(s):
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase PIRNR PIRNR001361
DAHP synthase PIRNR PIRNR001361
Phospho-2-keto-3-deoxyheptonate aldolase PIRNR PIRNR001361

Gene names

Name:	aroG EMBL EDK58908.1
ORF Names:	BMAJHU_0583 EMBL EDK58908.1

Organism

Burkholderia mallei JHU EMBL EDK58908.1

Taxonomic identifier

334803 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	357 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) By similarity. PIRNR PIRNR001361
Catalytic activity	Phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate. PIRNR PIRNR001361
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7. PIRNR PIRNR001361
Sequence similarities	Belongs to the class-I DAHP synthase family. PIRNR PIRNR001361

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis PIRNR PIRNR001361
Molecular function	Transferase PIRNR PIRNR001361 EMBL EDK58908.1
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	3-deoxy-7-phosphoheptulonate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5XUQ6 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: 9EEAEFE1A92C7D83	FASTA	357	38,820
	10 20 30 40 50 60 MPPHNTDDVR IRELKELTPP AHLIREFALG EAVSELIYNA RQAMHRILHG MDDRLIVIIG 70 80 90 100 110 120 PCSIHDTKAA LEYAGRLVQE RERFASELEI VMRVYFEKPR TTVGWKGLIN DPHLDNSFKI 130 140 150 160 170 180 NDGLRTAREL LLQINEMGLP AGTEYLDMIS PQYIADLISW GAIGARTTES QVHRELASGL 190 200 210 220 230 240 SCPVGFKNGT DGNVKIAVDA IKAASQPHHF LSVTKGDHSA IVSTAGNEDC HVILRGGKAP 250 260 270 280 290 300 NYDADSVNAA CADIGKAGLA ARLMIDASHA NSSKKHENQI PVCADIGRQI AAGDERIVGV 310 320 330 340 350 MVESHLVEGR QDLKEGCPLT YGQSITDACI NWDDSVKVLE GLAEAVKARR VARGSGN

References

[1]	DeShazer D., Woods D.E., Nierman W.C. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: JHU EMBL EDK58908.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS264109 Genomic DNA. Translation: EDK58908.1.
3D structure databases
ProteinModelPortal	A5XUQ6.
SMR	A5XUQ6. Positions 4-350.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	26941220. VBIBurMal67795_4106.
Phylogenomic databases
OMA	MDNSFKL.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR006218. DAHP1/KDSA. IPR006219. DHAP_synth_1. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR21225. AroFGH. 1 hit.
Pfam	PF00793. DAHP_synth_1. 1 hit. [Graphical view]
PIRSF	PIRSF001361. DAHP_synthase. 1 hit.
TIGRFAMs	TIGR00034. AroFGH. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5XUQ6_BURMA

Accession

Primary (citable) accession number: A5XUQ6

Entry history

Integrated into UniProtKB/TrEMBL:	July 10, 2007
Last sequence update:	July 10, 2007
Last modified:	January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)