A5XT52 (A5XT52_BURMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dethiobiotin synthase EMBL EDK60000.1
EC=6.3.3.3 EMBL EDK60000.1

Gene names

Name:	bioD EMBL EDK60000.1
ORF Names:	BMAJHU_B0981 EMBL EDK60000.1

Organism

Burkholderia mallei JHU EMBL EDK60000.1

Taxonomic identifier

334803 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	240 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring By similarity. SAAS SAAS004472
Catalytic activity	ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin. SAAS SAAS004472
Cofactor	Magnesium By similarity. SAAS SAAS004472
Pathway	Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2. SAAS SAAS004472
Subcellular location	Cytoplasm By similarity SAAS SAAS004472.

Ontologies

Keywords
Biological process	Biotin biosynthesis SAAS SAAS004472
Cellular component	Cytoplasm SAAS SAAS004472
Ligand	ATP-binding SAAS SAAS004472 Magnesium SAAS SAAS004472 Metal-binding SAAS SAAS004472 Nucleotide-binding
Molecular function	Ligase SAAS SAAS004472 EMBL EDK60000.1
Gene Ontology (GO)
Biological process	biotin biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW dethiobiotin synthase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5XT52 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: 5E28F2256905A6FB	FASTA	240	24,874
	10 20 30 40 50 60 MSAPLSLFVT GTDTEIGKTF VSAALLHGFA RAGLRAAAMK PVAAGAYERD GAWRNEDADQ 70 80 90 100 110 120 LDAAANVALP AAIRTPFLLK APAAPHIVAA REGVALDIGT IVDAHRRACE MADVIVVEGV 130 140 150 160 170 180 GGVRVPLADT RDTADLAVAL GLPVVLVVGV RLGCISHALL TAEAIAARGL PLAGWVANRI 190 200 210 220 230 240 DPAMPFADDN IDTLRAWLER EHRAPLLGAL AHMSPPSPDA ASHALDVNLL LNALRAAAPR

References

[1]	DeShazer D., Woods D.E., Nierman W.C. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: JHU EMBL EDK60000.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS264108 Genomic DNA. Translation: EDK60000.1.
3D structure databases
ProteinModelPortal	A5XT52.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	26940042. VBIBurMal67795_3092.
Phylogenomic databases
OMA	INPGLSH.
Family and domain databases
HAMAP	MF_00336. BioD. [Tree]
InterPro	IPR002586. CbiA_P_synth. IPR004472. DTB_synth_BioD. [Graphical view]
Pfam	PF01656. CbiA. 1 hit. [Graphical view]
PIRSF	PIRSF006755. DTB_synth. 1 hit.
TIGRFAMs	TIGR00347. BioD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5XT52_BURMA

Accession

Primary (citable) accession number: A5XT52

Entry history

Integrated into UniProtKB/TrEMBL:	July 10, 2007
Last sequence update:	July 10, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)