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A5WT05

- A5WT05_MYCTF

UniProt

A5WT05 - A5WT05_MYCTF

Protein

Glutamate decarboxylase

Gene

TBFG_13469

Organism
Mycobacterium tuberculosis (strain F11)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (28 Jul 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotation, Lyase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    BioCyciMTUB336982:GH7I-3501-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
    Gene namesi
    Ordered Locus Names:TBFG_13469Imported
    ORF Names:P426_03562Imported
    OrganismiMycobacterium tuberculosis (strain F11)Imported
    Taxonomic identifieri336982 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
    ProteomesiUP000000660: Chromosome

    PTM / Processingi

    Proteomic databases

    PRIDEiA5WT05.

    Interactioni

    Protein-protein interaction databases

    STRINGi336982.TBFG_13469.

    Structurei

    3D structure databases

    ProteinModelPortaliA5WT05.
    SMRiA5WT05. Positions 12-447.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0076.
    HOGENOMiHOG000070228.
    KOiK01580.
    OMAiPTFQINF.
    OrthoDBiEOG6TFCPW.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A5WT05-1 [UniParc]FASTAAdd to Basket

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    MSRSHPSVPA HSIAPAYTGR MFTAPVPALR MPDESMDPEA AYRFIHDELM    50
    LDGSSRLNLA TFVTTWMDPE AEKLMAETFD KNMIDKDEYP ATAAIEARCV 100
    SMVADLFHAE GLRDHDPTSA TGVSTIGSSE AVMLGGLALK WRWRQRVGSW 150
    KGRMPNLVMG SNVQVVWEKF CRYFDVEPRY LPMERGRYVI TPEQVLAAVD 200
    ENTIGVVAIL GTTYTGELEP IAEICAALDK LAAGGGVDVP VHVDAASGGF 250
    VVPFLHPDLV WDFRLPRVVS INVSGHKYGL TYPGVGFVVW RGPEHLPEDL 300
    VFRVNYLGGD MPTFTLNFSR PGNQVVGQYY NFLRLGRDGY TKVMQALSHT 350
    ARWLGDQLRE VDHCEVISDG SAIPVVSFRL AGDRGYTEFD VSHELRTFGW 400
    QVPAYTMPDN ATDVAVLRIV VREGLSADLA RALHDDAVTA LAALDKVKPG 450
    GHFDAQHFAH 460
    Length:460
    Mass (Da):50,780
    Last modified:July 28, 2009 - v1
    Checksum:iB5DA3156D4C7CB4F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000717 Genomic DNA. Translation: ABR07794.1.
    JLDC01000018 Genomic DNA. Translation: KBJ32600.1.
    RefSeqiYP_001289396.1. NC_009565.1.

    Genome annotation databases

    EnsemblBacteriaiABR07794; ABR07794; TBFG_13469.
    GeneIDi5224158.
    KEGGimtf:TBFG_13469.
    PATRICi18138454. VBIMycTub9078_3860.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000717 Genomic DNA. Translation: ABR07794.1 .
    JLDC01000018 Genomic DNA. Translation: KBJ32600.1 .
    RefSeqi YP_001289396.1. NC_009565.1.

    3D structure databases

    ProteinModelPortali A5WT05.
    SMRi A5WT05. Positions 12-447.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 336982.TBFG_13469.

    Proteomic databases

    PRIDEi A5WT05.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABR07794 ; ABR07794 ; TBFG_13469 .
    GeneIDi 5224158.
    KEGGi mtf:TBFG_13469.
    PATRICi 18138454. VBIMycTub9078_3860.

    Phylogenomic databases

    eggNOGi COG0076.
    HOGENOMi HOG000070228.
    KOi K01580.
    OMAi PTFQINF.
    OrthoDBi EOG6TFCPW.

    Enzyme and pathway databases

    BioCyci MTUB336982:GH7I-3501-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: F11Imported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: F11Imported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: F11Imported.

    Entry informationi

    Entry nameiA5WT05_MYCTF
    AccessioniPrimary (citable) accession number: A5WT05
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 28, 2009
    Last sequence update: July 28, 2009
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3