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A5WSE2 (A5WSE2_MYCTF) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210 RuleBase RU000531
EC=2.5.1.19 HAMAP MF_00210 RuleBase RU000531
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase HAMAP MF_00210
Gene names
Name:aroA HAMAP MF_00210
Ordered Locus Names:TBFG_13256
OrganismMycobacterium tuberculosis (strain F11) [Complete proteome] [HAMAP]
Taxonomic identifier336982 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length450 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210 RuleBase RU000531

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family. HAMAP MF_00210 RuleBase RU004164

Sequences

Sequence LengthMass (Da)Tools
A5WSE2 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: 27BB86F9412A07D5

FASTA45046,426
        10         20         30         40         50         60 
MKTWPAPTAP TPVRATVTVP GSKSQTNRAL VLAALAAAQG RGASTISGAL RSRDTELMLD 

        70         80         90        100        110        120 
ALQTLGLRVD GVGSELTVSG RIEPGPGARV DCGLAGTVLR FVPPLAALGS VPVTFDGDQQ 

       130        140        150        160        170        180 
ARGRPIAPLL DALRELGVAV DGTGLPFRVR GNGSLAGGTV AIDASASSQF VSGLLLSAAS 

       190        200        210        220        230        240 
FTDGLTVQHT GSSLPSAPHI AMTAAMLRQA GVDIDDSTPN RWQVRPGPVA ARRWDIEPDL 

       250        260        270        280        290        300 
TNAVAFLSAA VVSGGTVRIT GWPRVSVQPA DHILAILRQL NAVVIHADSS LEVRGPTGYD 

       310        320        330        340        350        360 
GFDVDLRAVG ELTPSVAALA ALASPGSVSR LSGIAHLRGH ETDRLAALST EINRLGGTCR 

       370        380        390        400        410        420 
ETPDGLVITA TPLRPGIWRA YADHRMAMAG AIIGLRVAGV EVDDIAATTK TLPEFPRLWA 

       430        440        450 
EMVGPGQGWG YPQPRSGQRA RRATGQGSGG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000717 Genomic DNA. Translation: ABR07581.1.
RefSeqYP_001289183.1. NC_009565.1.

3D structure databases

ProteinModelPortalA5WSE2.
SMRA5WSE2. Positions 1-424.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5WSE2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5223945.
GenomeReviewsGene locus TBFG_13256 in contig CP000717_GR.
KEGGmtf:TBFG_13256.
PATRIC18137999. VBIMycTub9078_3633.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAHRMATAG.
ProtClustDBPRK02427.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5WSE2_MYCTF
AccessionPrimary (citable) accession number: A5WSE2
Entry history
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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