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A5WR24 (A5WR24_MYCTF) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydrodipicolinate reductase HAMAP MF_00102
Short name=DHPR HAMAP MF_00102
EC=1.3.1.26 HAMAP MF_00102
Gene names
Name:dapB HAMAP MF_00102
Ordered Locus Names:TBFG_12786
OrganismMycobacterium tuberculosis (strain F11) [Complete proteome] [HAMAP]
Taxonomic identifier336982 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length245 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-2,3,4,5-tetrahydrodipicolinate + NAD(P)+ = (S)-2,3-dihydrodipicolinate + NAD(P)H. HAMAP MF_00102 SAAS SAAS022664

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4. HAMAP MF_00102 SAAS SAAS022664

Subcellular location

Cytoplasm By similarity HAMAP MF_00102 SAAS SAAS022664.

Sequence similarities

Belongs to the dihydrodipicolinate reductase family. HAMAP MF_00102

Sequences

Sequence LengthMass (Da)Tools
A5WR24 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: CDB8273AFFD4C095

FASTA24525,733
        10         20         30         40         50         60 
MRVGVLGAKG KVGATMVRAV AAADDLTLSA ELDAGDPLSL LTDGNTEVVI DFTHPDVVMG 

        70         80         90        100        110        120 
NLEFLIDNGI HAVVGTTGFT AERFQQVESW LVAKPNTSVL IAPNFAIGAV LSMHFAKQAA 

       130        140        150        160        170        180 
RFFDSAEVIE LHHPHKADAP SGTAARTAKL IAEARKGLPP NPDATSTSLP GARGADVDGI 

       190        200        210        220        230        240 
PVHAVRLAGL VAHQEVLFGT EGETLTIRHD SLDRTSFVPG VLLAVRRIAE RPGLTVGLEP 


LLDLH

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000717 Genomic DNA. Translation: ABR07113.1.
RefSeqYP_001288715.1. NC_009565.1.

3D structure databases

ProteinModelPortalA5WR24.
SMRA5WR24. Positions 2-245.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5WR24.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5223472.
GenomeReviewsGene locus TBFG_12786 in contig CP000717_GR.
KEGGmtf:TBFG_12786.
PATRIC18136941. VBIMycTub9078_3107.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMADRASFMP.
ProtClustDBPRK00048.

Family and domain databases

HAMAPMF_00102. DapB.
[Tree]
InterProIPR022663. DapB_C.
IPR000846. DapB_N.
IPR022664. DapB_N_CS.
IPR011770. Dihydrodipicolinate_Rdtase.
IPR023940. Dihydrodipicolinate_Rdtase_bac.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00215.
PANTHERPTHR20836. DapB_bac/pln. 1 hit.
PfamPF05173. DapB_C. 1 hit.
PF01113. DapB_N. 1 hit.
[Graphical view]
PIRSFPIRSF000161. DHPR. 1 hit.
TIGRFAMsTIGR00036. DapB. 1 hit.
PROSITEPS01298. DAPB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5WR24_MYCTF
AccessionPrimary (citable) accession number: A5WR24
Entry history
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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