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A5WQ91 (A5WQ91_MYCTF) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol-3-phosphate acyltransferase HAMAP MF_00393
Short name=GPAT HAMAP MF_00393
EC=2.3.1.15 HAMAP MF_00393
Gene names
Name:plsB HAMAP MF_00393
Ordered Locus Names:TBFG_12503
OrganismMycobacterium tuberculosis (strain F11) [Complete proteome] [HAMAP]
Taxonomic identifier336982 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length789 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate. HAMAP MF_00393 SAAS SAAS002123

Pathway

Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3. HAMAP MF_00393 SAAS SAAS002123

Subcellular location

Cell membrane; Peripheral membrane protein; Cytoplasmic side By similarity HAMAP MF_00393.

Domain

The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate By similarity. HAMAP MF_00393

Sequence similarities

Belongs to the GPAT/DAPAT family. HAMAP MF_00393

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif275 – 2806HXXXXD motif By similarity HAMAP MF_00393

Sequences

Sequence LengthMass (Da)Tools
A5WQ91 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: B78D7D9A9796EA22

FASTA78988,368
        10         20         30         40         50         60 
MTKPAADASA VLTAEDTLVL ASTATPVEME LIMGWLGQQR ARHPDSKFDI LKLPPRNAPP 

        70         80         90        100        110        120 
AALTALVEQL EPGFASSPQS GEDRSIVPVR VIWLPPADRS RAGKVAALLP GRDPYHPSQR 

       130        140        150        160        170        180 
QQRRILRTDP RRARVVAGES AKVSELRQQW RDTTVAEHKR DFAQFVSRRA LLALARAEYR 

       190        200        210        220        230        240 
ILGPQYKSPR LVKPEMLASA RFRAGLDRIP GATVEDAGKM LDELSTGWSQ VSVDLVSVLG 

       250        260        270        280        290        300 
RLASRGFDPE FDYDEYQVAA MRAALEAHPA VLLFSHRSYI DGVVVPVAMQ DNRLPPVHMF 

       310        320        330        340        350        360 
GGINLSFGLM GPLMRRSGMI FIRRNIGNDP LYKYVLKEYV GYVVEKRFNL SWSIEGTRSR 

       370        380        390        400        410        420 
TGKMLPPKLG LMSYVADAYL DGRSDDILLQ GVSICFDQLH EITEYAAYAR GAEKTPEGLR 

       430        440        450        460        470        480 
WLYNFIKAQG ERNFGKIYVR FPEAVSMRQY LGAPHGELTQ DPAAKRLALQ KMSFEVAWRI 

       490        500        510        520        530        540 
LQATPVTATG LVSALLLTTR GTALTLDQLH HTLQDSLDYL ERKQSPVSTS ALRLRSREGV 

       550        560        570        580        590        600 
RAAADALSNG HPVTRVDSGR EPVWYIAPDD EHAAAFYRNS VIHAFLETSI VELALAHAKH 

       610        620        630        640        650        660 
AEGDRVAAFW AQAMRLRDLL KFDFYFADST AFRANIAQEM AWHQDWEDHL GVGGNEIDAM 

       670        680        690        700        710        720 
LYAKRPLMSD AMLRVFFEAY EIVADVLRDA PPDIGPEELT ELALGLGRQF VAQGRVRSSE 

       730        740        750        760        770        780 
PVSTLLFATA RQVAVDQELI APAADLAERR VAFRRELRNI LRDFDYVEQI ARNQFVAREF 


KARQGRDRI

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000717 Genomic DNA. Translation: ABR06830.1.
RefSeqYP_001288432.1. NC_009565.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA5WQ91.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5223182.
GenomeReviewsGene locus TBFG_12503 in contig CP000717_GR.
KEGGmtf:TBFG_12503.
PATRIC18136305. VBIMycTub9078_2796.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAIVPVAMQ.
ProtClustDBPRK03355.

Family and domain databases

HAMAPMF_00393. Glyc3P_acyltrans.
[Tree]
InterProIPR002123. Acyltransferase.
IPR022284. G3P_O-AcylTrfase.
[Graphical view]
KOK00631.
PfamPF01553. Acyltransferase. 1 hit.
[Graphical view]
PIRSFPIRSF000437. GPAT_DHAPAT. 1 hit.
SMARTSM00563. PlsC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5WQ91_MYCTF
AccessionPrimary (citable) accession number: A5WQ91
Entry history
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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