A5WM72 (A5WM72_MYCTF) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Guanylate kinase gmk EMBL ABR05761.1

Gene names

Ordered Locus Names:

TBFG_11418

Organism

Mycobacterium tuberculosis (strain F11) [Complete proteome] [HAMAP]

Taxonomic identifier

336982 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	217 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Essential for recycling GMP and indirectly, cGMP By similarity. SAAS SAAS020590
Catalytic activity	ATP + GMP = ADP + GDP. SAAS SAAS020590
Subcellular location	Cytoplasm By similarity SAAS SAAS020590.
Sequence similarities	Contains 1 guanylate kinase-like domain. SAAS SAAS017665

Ontologies

Keywords
Cellular component	Cytoplasm SAAS SAAS020590
Ligand	ATP-binding SAAS SAAS020590 Nucleotide-binding
Molecular function	Kinase SAAS SAAS020590 EMBL ABR05761.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine nucleotide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW guanylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5WM72 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: 8569B30C989B9874	FASTA	217	22,888
	10 20 30 40 50 60 MGGTRPGAPV SVGEGPDTKP TARGQPAAVG RVVVLSGPSA VGKSTVVRCL RERIPNLHFS 70 80 90 100 110 120 VSATTRAPRP GEVDGVDYHF IDPTRFQQLI DQGELLEWAE IHGGLHRSGT LAQPVRAAAA 130 140 150 160 170 180 TGVPVLIEVD LAGARAIKKT MPEAVTVFLA PPSWQDLQAR LIGRGTETAD VIQRRLDTAR 190 200 210 IELAAQGDFD KVVVNRRLES ACAELVSLLV GTAPGSP

References

[1]

"The complete genome sequence of Mycobacterium tuberculosis F11." Birren B., Lander E., Galagan J., Devon K., Nusbaum C., Borowsky M.L., Grabherr M., Mauceli E., Brockman W., Young S., LaButti K., Pushparaj V., Sykes S., Baldwin J., Fitzgerald M., Bloom T., Zimmer A., Settipalli S. , Shea T., Arachchi H., Macdonald P., Abouelleil A., Lui A., Priest M., Berlin A., Gearin G., Brown A., Aftuck L., Bessette D., Allen N., Lubonja R., Lokyitsang T., Matthews C., Dunbar C., Benamara M., Nguyen T., Negash T., DeCaprio D., Crawford M., Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C., Kodira C., Zeng Q., Yandava C., O'Leary S., Alvarado L., Victor T., Murray M. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000717 Genomic DNA. Translation: ABR05761.1.
RefSeq	YP_001287363.1. NC_009565.1.
3D structure databases
ProteinModelPortal	A5WM72.
SMR	A5WM72. Positions 29-211.
ModBase	Search...
Protein-protein interaction databases
STRING	A5WM72.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5222097.
GenomeReviews	Gene locus TBFG_11418 in contig CP000717_GR.
KEGG	mtf:TBFG_11418.
PATRIC	18133803. VBIMycTub9078_1555.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	EWAEFAG.
ProtClustDB	PRK00300.
Family and domain databases
HAMAP	MF_00328. Guanylate_kinase. [Tree]
InterPro	IPR008144. Guanylate_kin. IPR008145. Guanylate_kin/L-typ_Ca_channel. IPR020590. Guanylate_kinase_CS. IPR017665. Guanylate_kinase_sub. [Graphical view]
KO	K00942.
Pfam	PF00625. Guanylate_kin. 1 hit. [Graphical view]
SMART	SM00072. GuKc. 1 hit. [Graphical view]
TIGRFAMs	TIGR03263. Guanyl_kin. 1 hit.
PROSITE	PS00856. GUANYLATE_KINASE_1. 1 hit. PS50052. GUANYLATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5WM72_MYCTF

Accession

Primary (citable) accession number: A5WM72

Entry history

Integrated into UniProtKB/TrEMBL:	July 28, 2009
Last sequence update:	July 28, 2009
Last modified:	December 14, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)