A5WK84 (A5WK84_MYCTF) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
50S ribosomal protein L5 HAMAP MF_01333 RuleBase RU003931

Gene names

Name:	rplE HAMAP MF_01333
Ordered Locus Names:	TBFG_10730

Organism

Mycobacterium tuberculosis (strain F11) [Complete proteome] [HAMAP]

Taxonomic identifier

336982 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	187 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement By similarity. RuleBase RU003931 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs By similarity. HAMAP MF_01333
Subunit structure	Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome By similarity. HAMAP MF_01333
Sequence similarities	Belongs to the ribosomal protein L5P family. HAMAP MF_01333 RuleBase RU003930

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding HAMAP MF_01333 RuleBase RU003931 tRNA-binding HAMAP MF_01333 RuleBase RU003931
Molecular function	Ribonucleoprotein Ribosomal protein HAMAP MF_01333 RuleBase RU003930 EMBL ABR05073.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5WK84 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: CFC6FDB2718308BC	FASTA	187	21,019
	10 20 30 40 50 60 MTTAQKVQPR LKERYRSEIR DALRKQFGYG NVMQIPTVTK VVVNMGVGEA ARDAKLINGA 70 80 90 100 110 120 VNDLALITGQ KPEVRRARKS IAQFKLREGM PVGVRVTLRG DRMWEFLDRL TSIALPRIRD 130 140 150 160 170 180 FRGLSPKQFD GVGNYTFGLA EQAVFHEVDV DKIDRVRGMD INVVTSAATD DEGRALLRAL GFPFKEN

References

[1]

"The complete genome sequence of Mycobacterium tuberculosis F11." Birren B., Lander E., Galagan J., Devon K., Nusbaum C., Borowsky M.L., Grabherr M., Mauceli E., Brockman W., Young S., LaButti K., Pushparaj V., Sykes S., Baldwin J., Fitzgerald M., Bloom T., Zimmer A., Settipalli S. , Shea T., Arachchi H., Macdonald P., Abouelleil A., Lui A., Priest M., Berlin A., Gearin G., Brown A., Aftuck L., Bessette D., Allen N., Lubonja R., Lokyitsang T., Matthews C., Dunbar C., Benamara M., Nguyen T., Negash T., DeCaprio D., Crawford M., Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C., Kodira C., Zeng Q., Yandava C., O'Leary S., Alvarado L., Victor T., Murray M. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000717 Genomic DNA. Translation: ABR05073.1.
RefSeq	YP_001286675.1. NC_009565.1.
3D structure databases
ProteinModelPortal	A5WK84.
SMR	A5WK84. Positions 8-186.
ModBase	Search...
Protein-protein interaction databases
STRING	A5WK84.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5221398.
GenomeReviews	Gene locus TBFG_10730 in contig CP000717_GR.
KEGG	mtf:TBFG_10730.
PATRIC	18132262. VBIMycTub9078_0800.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	RQGMPIG.
ProtClustDB	PRK00010.
Family and domain databases
HAMAP	MF_01333_B. Ribosomal_L5_B. [Tree]
InterPro	IPR002132. Ribosomal_L5. IPR020930. Ribosomal_L5_bac-type. IPR022803. Ribosomal_L5_domain. [Graphical view]
Gene3D	G3DSA:3.30.1440.10. Ribosomal_L5. 1 hit.
KO	K02931.
PANTHER	PTHR11994. Ribosomal_L5. 1 hit.
Pfam	PF00281. Ribosomal_L5. 1 hit. PF00673. Ribosomal_L5_C. 1 hit. [Graphical view]
PIRSF	PIRSF002161. Ribosomal_L5. 1 hit.
SUPFAM	SSF55282. Ribosomal_L5. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5WK84_MYCTF

Accession

Primary (citable) accession number: A5WK84

Entry history

Integrated into UniProtKB/TrEMBL:	July 28, 2009
Last sequence update:	July 28, 2009
Last modified:	December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)