A5WIG8 (A5WIG8_MYCTF) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Sedoheptulose-7-phosphate isomerase gmhA EMBL ABR04457.1

Gene names

Ordered Locus Names:

TBFG_10114

Organism

Mycobacterium tuberculosis (strain F11) [Complete proteome] [HAMAP]

Taxonomic identifier

336982 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	196 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate By similarity. SAAS SAAS020620
Catalytic activity	D-sedoheptulose 7-phosphate = D-glycero-D-manno-heptose 7-phosphate. SAAS SAAS020620
Cofactor	Binds 1 zinc ion per subunit By similarity. SAAS SAAS020620
Pathway	Carbohydrate biosynthesis; D-glycero-D-manno-heptose 7-phosphate biosynthesis; D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate from sedoheptulose 7-phosphate: step 1/1. SAAS SAAS020620
Subcellular location	Cytoplasm By similarity SAAS SAAS020620.
Sequence similarities	Contains 1 SIS domain. SAAS SAAS020620

Ontologies

Keywords
Biological process	Carbohydrate metabolism SAAS SAAS020620
Cellular component	Cytoplasm SAAS SAAS020620
Ligand	Metal-binding SAAS SAAS020620 Zinc SAAS SAAS020620
Molecular function	Isomerase SAAS SAAS020620 EMBL ABR04457.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	D-sedoheptulose 7-phosphate isomerase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW sugar binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5WIG8 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: 0F05EB968F1189CB	FASTA	196	20,923
	10 20 30 40 50 60 MCTARTAEEI FVETIAVKTR ILNDRVLLEA ARAIGDRLIA GYRAGARVFM CGNGGSAADA 70 80 90 100 110 120 QHFAAELTGH LIFDRPPLGA EALHANSSHL TAVANDYDYD TVFARALEGS ARPGDTLFAI 130 140 150 160 170 180 STSGNSMSVL RAAKTARELG VTVVAMTGES GGQLAEFADF LINVPSRDTG RIQESHIVFI 190 HAISEHVEHA LFAPRQ

References

[1]

"The complete genome sequence of Mycobacterium tuberculosis F11." Birren B., Lander E., Galagan J., Devon K., Nusbaum C., Borowsky M.L., Grabherr M., Mauceli E., Brockman W., Young S., LaButti K., Pushparaj V., Sykes S., Baldwin J., Fitzgerald M., Bloom T., Zimmer A., Settipalli S. , Shea T., Arachchi H., Macdonald P., Abouelleil A., Lui A., Priest M., Berlin A., Gearin G., Brown A., Aftuck L., Bessette D., Allen N., Lubonja R., Lokyitsang T., Matthews C., Dunbar C., Benamara M., Nguyen T., Negash T., DeCaprio D., Crawford M., Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C., Kodira C., Zeng Q., Yandava C., O'Leary S., Alvarado L., Victor T., Murray M. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000717 Genomic DNA. Translation: ABR04457.1.
RefSeq	YP_001286059.1. NC_009565.1.
3D structure databases
ProteinModelPortal	A5WIG8.
ModBase	Search...
Protein-protein interaction databases
STRING	A5WIG8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5220777.
GenomeReviews	Gene locus TBFG_10114 in contig CP000717_GR.
KEGG	mtf:TBFG_10114.
PATRIC	18130903. VBIMycTub9078_0125.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	HITIIHI.
ProtClustDB	PRK13938.
Family and domain databases
HAMAP	MF_00067. GmhA. [Tree]
InterPro	IPR020620. Phosphoheptose_isomerase. IPR001347. SIS. [Graphical view]
KO	K03271.
Pfam	PF01380. SIS. 1 hit. [Graphical view]
PROSITE	PS51464. SIS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5WIG8_MYCTF

Accession

Primary (citable) accession number: A5WIG8

Entry history

Integrated into UniProtKB/TrEMBL:	July 28, 2009
Last sequence update:	July 28, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)