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A5WG08

- ASSY_PSYWF

UniProt

A5WG08 - ASSY_PSYWF

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Protein
Argininosuccinate synthase
Gene
argG, PsycPRwf_1659
Organism
Psychrobacter sp. (strain PRwf-1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei42 – 421ATP; via amide nitrogen and carbonyl oxygen By similarity
Binding sitei93 – 931Citrulline By similarity
Binding sitei98 – 981Citrulline By similarity
Binding sitei123 – 1231ATP; via amide nitrogen By similarity
Binding sitei125 – 1251Aspartate By similarity
Binding sitei129 – 1291Aspartate By similarity
Binding sitei129 – 1291Citrulline By similarity
Binding sitei130 – 1301Aspartate By similarity
Binding sitei133 – 1331Citrulline By similarity
Binding sitei185 – 1851Citrulline By similarity
Binding sitei194 – 1941Citrulline By similarity
Binding sitei270 – 2701Citrulline By similarity
Binding sitei282 – 2821Citrulline By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 239ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. argininosuccinate synthase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPPRW349106:GHZF-1690-MONOMER.
UniPathwayiUPA00068; UER00113.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate synthase (EC:6.3.4.5)
Alternative name(s):
Citrulline--aspartate ligase
Gene namesi
Name:argG
Ordered Locus Names:PsycPRwf_1659
OrganismiPsychrobacter sp. (strain PRwf-1)
Taxonomic identifieri349106 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaePsychrobacter
ProteomesiUP000001993: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 411411Argininosuccinate synthaseUniRule annotation
PRO_1000070915Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi349106.PsycPRwf_1659.

Structurei

3D structure databases

ProteinModelPortaliA5WG08.
SMRiA5WG08. Positions 11-404.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0137.
HOGENOMiHOG000230093.
KOiK01940.
OMAiAPPEEAY.
OrthoDBiEOG6K9QCV.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPiMF_00005. Arg_succ_synth_type1.
InterProiIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00032. argG. 1 hit.
PROSITEiPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5WG08-1 [UniParc]FASTAAdd to Basket

« Hide

MSIENKDNIN KIVLAYSGGL DTSIIAKWLQ DTYDAEVITF TADIGQGEEV    50
EPARAKAEAM GIKHIHIEDL RAEFARDYVF PMFRANAIYE GEYLLGTSIA 100
RPLIAKRLVE IAKEHNADAI SHGATGKGND QVRFELGAIA LAPDVKTIAP 150
WREWDLSSRE SLMAYAKEHN IPIDFAANKK KSPYSMDANL LHISYEGDIL 200
EDPYAEAEDD MWRWSVSPEQ APDTPEYLEL EYEKGDIVAI NGEKLEPYEV 250
MIKLNELGGK HGIGRLDIVE NRYVGMKSRG CYETPAGTIM LKAHRGMESL 300
TLDREAAHLK DELMPRYAKI IYNGYWFSPE RQMLQALIDK SQEYVTGTVR 350
VKLYKGNVSV VGRKSPYSLF DEKIATFEDD AGAYDQKDAE GFIRLNGLRL 400
SIEASRGRDL S 411
Length:411
Mass (Da):46,272
Last modified:July 10, 2007 - v1
Checksum:iB71C5B6CD5AF8A35
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000713 Genomic DNA. Translation: ABQ94599.1.
RefSeqiWP_011960877.1. NC_009524.1.
YP_001280549.1. NC_009524.1.

Genome annotation databases

EnsemblBacteriaiABQ94599; ABQ94599; PsycPRwf_1659.
GeneIDi5205349.
KEGGiprw:PsycPRwf_1659.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000713 Genomic DNA. Translation: ABQ94599.1 .
RefSeqi WP_011960877.1. NC_009524.1.
YP_001280549.1. NC_009524.1.

3D structure databases

ProteinModelPortali A5WG08.
SMRi A5WG08. Positions 11-404.
ModBasei Search...

Protein-protein interaction databases

STRINGi 349106.PsycPRwf_1659.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABQ94599 ; ABQ94599 ; PsycPRwf_1659 .
GeneIDi 5205349.
KEGGi prw:PsycPRwf_1659.

Phylogenomic databases

eggNOGi COG0137.
HOGENOMi HOG000230093.
KOi K01940.
OMAi APPEEAY.
OrthoDBi EOG6K9QCV.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00113 .
BioCyci PPRW349106:GHZF-1690-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPi MF_00005. Arg_succ_synth_type1.
InterProi IPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF00764. Arginosuc_synth. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00032. argG. 1 hit.
PROSITEi PS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PRwf-1.

Entry informationi

Entry nameiASSY_PSYWF
AccessioniPrimary (citable) accession number: A5WG08
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: July 10, 2007
Last modified: September 3, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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