A5WCR8 (A5WCR8_PSYWF) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Histidinol-phosphate aminotransferase 1 HAMAP MF_01023
EC=2.6.1.9 HAMAP MF_01023

Alternative name(s):
Imidazole acetol-phosphate transaminase 1 HAMAP MF_01023

Gene names

Name:	hisC1 HAMAP MF_01023
Ordered Locus Names:	PsycPRwf_0504

Organism

Psychrobacter sp. (strain PRwf-1) [Complete proteome] [HAMAP] EMBL ABQ93459.1

Taxonomic identifier

349106 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Psychrobacter

Protein attributes

Sequence length	367 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023 SAAS SAAS005861
Cofactor	Pyridoxal phosphate By similarity. HAMAP MF_01023 SAAS SAAS005861
Pathway	Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023 SAAS SAAS005861
Subunit structure	Homodimer By similarity. HAMAP MF_01023
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP MF_01023

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Histidine biosynthesis HAMAP MF_01023 SAAS SAAS005861
Ligand	Pyridoxal phosphate HAMAP MF_01023 SAAS SAAS005861
Molecular function	Aminotransferase HAMAP MF_01023 SAAS SAAS005861 EMBL ABQ93459.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	L-phenylalanine:2-oxoglutarate aminotransferase activity Inferred from electronic annotation. Source: EC histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Modified residue	225	1	N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01023

Sequences

	Sequence		Length	Mass (Da)
	A5WCR8 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: 1B3499E6E0C1654F	FASTA	367	40,806
	10 20 30 40 50 60 MIKTMEFKLD TRLWSTKARN LNPYVPGEQP KHDNLCKLNT NENPFPPSPK VVEAITAALS 70 80 90 100 110 120 HGGDQLRLYP APESDALRQA LADAYDLQLN QVFVGNGSDE VLALVFASFF MKERPLLAPD 130 140 150 160 170 180 ISYSFYPVYA DTFGIDLVKI PLRDDFSIET DDYRQPCSGI IIANPNAPTG ILMSLEAIDK 190 200 210 220 230 240 LATEHPNAVI VIDEAYIDFA STEQASAIRL IETHDNLLVT QTFSKSRSLA GLRVGMAFGN 250 260 270 280 290 300 PSLIEALTRM KNSFNSYPLD RLAQAGALAS VEDKLYFKST CEQVIALREQ LIEQLSSLNF 310 320 330 340 350 360 TVLPSQANFV FARPQQGNAS EVAQQLREQG IIVRYFNQPR INEYLRITVG TAEQNRRLIG ALQQMAG

References

[1]

"Complete sequence of chromosome of Psychrobacter sp. PRwf-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P. Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PRwf-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000713 Genomic DNA. Translation: ABQ93459.1.
RefSeq	YP_001279409.1. NC_009524.1.
3D structure databases
ProteinModelPortal	A5WCR8.
ModBase	Search...
Protein-protein interaction databases
STRING	A5WCR8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5205394.
GenomeReviews	Gene locus PsycPRwf_0504 in contig CP000713_GR.
KEGG	prw:PsycPRwf_0504.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0079.
HOGENOM	HBG646350.
OMA	MKNSFNS.
ProtClustDB	PRK05387.
Enzyme and pathway databases
BioCyc	PSP56811:PSYCPRWF_0504-MONOMER.
Family and domain databases
HAMAP	MF_01023. HisC_aminotrans_2. [Tree]
InterPro	IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00817.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01141. HisC. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5WCR8_PSYWF

Accession

Primary (citable) accession number: A5WCR8

Entry history

Integrated into UniProtKB/TrEMBL:	July 10, 2007
Last sequence update:	July 10, 2007
Last modified:	November 16, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)