A5WBN8 (A5WBN8_PSYWF) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Shikimate dehydrogenase HAMAP MF_00222
EC=1.1.1.25 HAMAP MF_00222

Gene names

Name:	aroE HAMAP MF_00222
Ordered Locus Names:	PsycPRwf_0119

Organism

Psychrobacter sp. (strain PRwf-1) [Complete proteome] [HAMAP] EMBL ABQ93079.1

Taxonomic identifier

349106 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Psychrobacter

Protein attributes

Sequence length	294 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Shikimate + NADP+ = 3-dehydroshikimate + NADPH. HAMAP MF_00222
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. HAMAP MF_00222
Sequence similarities	Belongs to the shikimate dehydrogenase family. HAMAP MF_00222

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00222
Ligand	NADP HAMAP MF_00222
Molecular function	Oxidoreductase HAMAP MF_00222 EMBL ABQ93079.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro shikimate 3-dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	155 – 159	5	NADP By similarity HAMAP MF_00222
Sites
	Active site	92	1	Proton acceptor By similarity HAMAP MF_00222

Sequences

	Sequence		Length	Mass (Da)
	A5WBN8 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: 2CD53EBEB2E2AAA5	FASTA	294	31,301
	10 20 30 40 50 60 MSPSDISRNL TIDSNSDTKC SVDAQTQHFM VIGNPIAHSK SPQIHQQFAK QTGLDIRYAR 70 80 90 100 110 120 QYCPDDKASF TAVVEAFFNG GGVGANVTVP FKQIAYQMCA EQGGLSAHAQ VAGAVNTLLL 130 140 150 160 170 180 KDGKLFGDNT DGQGLVNHLR QLGWPLQGAK VAILGAGGAS RGVVLPLIEA GISELTIANR 190 200 210 220 230 240 TLSKAEDLID QLCSAHPLIA TIAPTSCTIE ALTGQYDLII NATSIGLSGD SLPLREALRC 250 260 270 280 290 GYAYDMMYGR ELPFLTHFHS HSAQVSEGYG MLIGQAALSF TQWTGKAVDS NLFI

References

[1]

"Complete sequence of chromosome of Psychrobacter sp. PRwf-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P. Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PRwf-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000713 Genomic DNA. Translation: ABQ93079.1.
RefSeq	YP_001279029.1. NC_009524.1.
3D structure databases
ProteinModelPortal	A5WBN8.
ModBase	Search...
Protein-protein interaction databases
STRING	A5WBN8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5205508.
GenomeReviews	Gene locus PsycPRwf_0119 in contig CP000713_GR.
KEGG	prw:PsycPRwf_0119.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0169.
HOGENOM	HBG553408.
OMA	VVFGNPI.
ProtClustDB	CLSK838830.
Enzyme and pathway databases
BioCyc	PSP56811:PSYCPRWF_0119-MONOMER.
Family and domain databases
HAMAP	MF_00222. Shikimate_DH_AroE. [Tree]
InterPro	IPR016040. NAD(P)-bd_dom. IPR011342. Shikimate_DH. IPR013708. Shikimate_DH-bd_N. IPR022893. Shikimate_quinate_DH. IPR006151. Shikm_DH/Glu-tRNA_Rdtase. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00014.
Pfam	PF01488. Shikimate_DH. 1 hit. PF08501. Shikimate_dh_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00507. AroE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5WBN8_PSYWF

Accession

Primary (citable) accession number: A5WBN8

Entry history

Integrated into UniProtKB/TrEMBL:	July 10, 2007
Last sequence update:	July 10, 2007
Last modified:	December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)