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A5W9Q6

- PNCB_PSEP1

UniProt

A5W9Q6 - PNCB_PSEP1

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Protein
Nicotinate phosphoribosyltransferase
Gene
pncB, Pput_4746
Organism
Pseudomonas putida (strain F1 / ATCC 700007)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate phosphoribosyltransferase activity Source: InterPro
  3. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

BioCyciPPUT351746:GI26-4837-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferase (EC:6.3.4.21)
Short name:
NAPRTase
Gene namesi
Name:pncB
Ordered Locus Names:Pput_4746
OrganismiPseudomonas putida (strain F1 / ATCC 700007)
Taxonomic identifieri351746 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000006553: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 401401Nicotinate phosphoribosyltransferaseUniRule annotation
PRO_1000025006Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi351746.Pput_4746.

Structurei

3D structure databases

ProteinModelPortaliA5W9Q6.
SMRiA5W9Q6. Positions 1-397.

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000284928.
KOiK00763.
OMAiQAVFHRY.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

A5W9Q6-1 [UniParc]FASTAAdd to Basket

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MSESAFAERI VHNLLDTDFY KLTMMQGVLH NYPDADVEWE FRCRNGEDLR    50
PYLGEIRNQL ERLGDLTLDD GQLAFLERIS FLKPDFLRFL RLFRFNLRYV 100
HVGIENDQLF LRLKGPWLHV ILFEVPLLAI ISEVRNRNLH PHMRLAEARD 150
QLYRKFDWLR AHASDDELAE LQVADFGTRR RFSSRVQEEV VRVLRDDFPG 200
RFVGTSNVDL AWKLDIKPLG TMAHEWIMAH QQLGPRLIDS QIAALDCWVR 250
EYRGLLGIAL TDCITMDAFL GDFDLYFAKL FDGLRHDSGE PVAWAEKAIA 300
HYQKLGIDPM TKTLVFSDGL NLTRSLEIFR ALRGRINVSF GIGTNLTCDI 350
PGVAPMSIVL KMTDCNGAPV AKISDEAAKT QCRDENFVAY MRHVFKVPSK 400
E 401
Length:401
Mass (Da):46,205
Last modified:July 10, 2007 - v1
Checksum:iF1698FF50D94B7AB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000712 Genomic DNA. Translation: ABQ80866.1.
RefSeqiYP_001270050.1. NC_009512.1.

Genome annotation databases

EnsemblBacteriaiABQ80866; ABQ80866; Pput_4746.
GeneIDi5191695.
KEGGippf:Pput_4746.
PATRICi19925744. VBIPsePut56420_4814.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000712 Genomic DNA. Translation: ABQ80866.1 .
RefSeqi YP_001270050.1. NC_009512.1.

3D structure databases

ProteinModelPortali A5W9Q6.
SMRi A5W9Q6. Positions 1-397.
ModBasei Search...

Protein-protein interaction databases

STRINGi 351746.Pput_4746.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABQ80866 ; ABQ80866 ; Pput_4746 .
GeneIDi 5191695.
KEGGi ppf:Pput_4746.
PATRICi 19925744. VBIPsePut56420_4814.

Phylogenomic databases

eggNOGi COG1488.
HOGENOMi HOG000284928.
KOi K00763.
OMAi QAVFHRY.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .
BioCyci PPUT351746:GI26-4837-MONOMER.

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: F1 / ATCC 700007.

Entry informationi

Entry nameiPNCB_PSEP1
AccessioniPrimary (citable) accession number: A5W9Q6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 10, 2007
Last modified: September 3, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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