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A5W977 (A5W977_PSEP1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A synthetase 2 HAMAP MF_01123
EC=6.2.1.1 HAMAP MF_01123
Alternative name(s):
Acetate--CoA ligase 2 HAMAP MF_01123
Acyl-activating enzyme 2 HAMAP MF_01123
Gene names
Name:acsA2 HAMAP MF_01123
Ordered Locus Names:Pput_4567
OrganismPseudomonas putida (strain F1 / ATCC 700007) [Complete proteome] [HAMAP] EMBL ABQ80687.1
Taxonomic identifier351746 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length644 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA. HAMAP MF_01123

Post-translational modification

Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme By similarity. HAMAP MF_01123

Sequence similarities

Belongs to the ATP-dependent AMP-binding enzyme family. HAMAP MF_01123

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site5131 By similarity HAMAP MF_01123

Amino acid modifications

Modified residue6051N6-acetyllysine By similarity HAMAP MF_01123

Sequences

Sequence LengthMass (Da)Tools
A5W977 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 5C198DAD790AA2B7

FASTA64471,238
        10         20         30         40         50         60 
MFDIRKYPQA LAVSQSAALT PEDYRRLYRQ SVEDPDTFWA EQAKRLDWIK PWSSVQQCDL 

        70         80         90        100        110        120 
HTGKARWFDG AQLNVSYNCI DRHLAQRGEQ TALLWEGDDP KDSKAITYRE LHREVCRLAN 

       130        140        150        160        170        180 
AMKARGVKKG DRVCIYMPMI PEAAFAMLAC TRIGAIHSVV FGGFSPDALR DRILDADCRT 

       190        200        210        220        230        240 
VITADEGVRG GKRIPLKQNV DKALASCPAV SSVLVVRRTG GDVAWTEGRD LWYHEATKDA 

       250        260        270        280        290        300 
GDDCPPEPME AEDPLFILYT SGSTGKPKGV LHTTGGYLLQ ATMTFKVVFD YRDGEVFWCT 

       310        320        330        340        350        360 
ADVGWVTGHS YIVYGPLANG AISLMFEGVP NYPDTSRFWQ VVDKHQVNIF YTAPTALRAL 

       370        380        390        400        410        420 
MREGSAPLQG TSRKSLRLLG SVGEPINPEA WEWYFEEVGQ KRCPIVDTWW QTETGGIMLT 

       430        440        450        460        470        480 
PLPGTQSLKP GCATQPMFGV QPVLLDEKGK LIEGPGAGVL AIKASWPGQI RSVYGDHQRM 

       490        500        510        520        530        540 
VDTYFKPLPG YYFTGDGARR DADGDYWITG RIDDVINVSG HRIGTAEVES ALVLHDSVAE 

       550        560        570        580        590        600 
AAVVGYPHDL KGQGVYAFVT TMNGVTPDDT LKAELLALVS KEIGSFAKPE LIQWAPALPK 

       610        620        630        640 
TRSGKIMRRI LRKIACNELE NLGDTSTLAD PSVVQGLIDK RLNQ

« Hide

References

[1]"Complete sequence of Pseudomonas putida F1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Lykidis A., Parales R., Richardson P.
Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: F1 / ATCC 700007.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000712 Genomic DNA. Translation: ABQ80687.1.
RefSeqYP_001269871.1. NC_009512.1.

3D structure databases

ProteinModelPortalA5W977.
SMRA5W977. Positions 13-641.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5W977.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5194703.
GenomeReviewsGene locus Pput_4567 in contig CP000712_GR.
KEGGppf:Pput_4567.
PATRIC19925374. VBIPsePut56420_4631.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0365.
HOGENOMHBG547964.
OMAHQRMVDT.
ProtClustDBPRK00174.

Enzyme and pathway databases

BioCycPPUT351746:PPUT_4567-MONOMER.

Family and domain databases

HAMAPMF_01123. Ac_CoA_synth.
[Tree]
InterProIPR011904. Ac_CoA_lig.
IPR024597. Acyl-CoA_synth_DUF3448.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
KOK01895.
PANTHERPTHR24095:SF42. PTHR24095:SF42. 1 hit.
PfamPF00501. AMP-binding. 1 hit.
PF11930. DUF3448. 1 hit.
[Graphical view]
TIGRFAMsTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5W977_PSEP1
AccessionPrimary (citable) accession number: A5W977
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info