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Protein

Phosphonoacetaldehyde hydrolase

Gene

phnX

Organism
Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in phosphonate degradation.UniRule annotation

Catalytic activityi

Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 1 Mg2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei15NucleophileUniRule annotation1
Metal bindingi15MagnesiumUniRule annotation1
Metal bindingi17Magnesium; via carbonyl oxygenUniRule annotation1
Active sitei56Schiff-base intermediate with substrateUniRule annotation1
Metal bindingi189MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Magnesium, Metal-binding, Schiff base

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphonoacetaldehyde hydrolaseUniRule annotation (EC:3.11.1.1UniRule annotation)
Short name:
PhosphonataseUniRule annotation
Alternative name(s):
Phosphonoacetaldehyde phosphonohydrolaseUniRule annotation
Gene namesi
Name:phnXUniRule annotation
Ordered Locus Names:Pput_3530
OrganismiPseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)
Taxonomic identifieri351746 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000006553 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000682401 – 275Phosphonoacetaldehyde hydrolaseAdd BLAST275

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi351746.Pput_3530.

Structurei

3D structure databases

ProteinModelPortaliA5W696.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HAD-like hydrolase superfamily. PhnX family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108KAZ. Bacteria.
COG0637. LUCA.
HOGENOMiHOG000217971.
KOiK05306.
OMAiKAVIFDW.

Family and domain databases

Gene3Di1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPiMF_01375. PhnX. 1 hit.
InterProiIPR023214. HAD-like_dom.
IPR006439. HAD-SF_hydro_IA.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view]
PfamiPF13419. HAD_2. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01509. HAD-SF-IA-v3. 1 hit.
TIGR01422. phosphonatase. 1 hit.

Sequencei

Sequence statusi: Complete.

A5W696-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNYNNPTQLQ AAILDWAGTV VDFGSFAPTQ IFVEAFAEFD VQVSIEEARG
60 70 80 90 100
PMGMGKWDHI RTLCDVPEIA ERYRKVFGRT PTDDDVTAIY NRFMPLQIEK
110 120 130 140 150
IAVHSALIPG ALDTLTGLRQ DGLKIGSCSG YPKVVMDKVV ELAAQNGYVA
160 170 180 190 200
DHVVATDETP NGRPWPAQAL ANVIALGIDD VAACVKVDDT VPGILEGRRA
210 220 230 240 250
GMWTVALVCS GNALGLTWEG FRALSAEKLE SERQRIHALF AGSRPHYLID
260 270
TINDLPEVIA DINRRLAKGE MPQAF
Length:275
Mass (Da):30,051
Last modified:July 10, 2007 - v1
Checksum:i3E17780EDD2DDEB9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000712 Genomic DNA. Translation: ABQ79656.1.
RefSeqiWP_003250077.1. NC_009512.1.

Genome annotation databases

EnsemblBacteriaiABQ79656; ABQ79656; Pput_3530.
KEGGippf:Pput_3530.
PATRICi19923217. VBIPsePut56420_3580.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000712 Genomic DNA. Translation: ABQ79656.1.
RefSeqiWP_003250077.1. NC_009512.1.

3D structure databases

ProteinModelPortaliA5W696.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi351746.Pput_3530.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ79656; ABQ79656; Pput_3530.
KEGGippf:Pput_3530.
PATRICi19923217. VBIPsePut56420_3580.

Phylogenomic databases

eggNOGiENOG4108KAZ. Bacteria.
COG0637. LUCA.
HOGENOMiHOG000217971.
KOiK05306.
OMAiKAVIFDW.

Family and domain databases

Gene3Di1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPiMF_01375. PhnX. 1 hit.
InterProiIPR023214. HAD-like_dom.
IPR006439. HAD-SF_hydro_IA.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view]
PfamiPF13419. HAD_2. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01509. HAD-SF-IA-v3. 1 hit.
TIGR01422. phosphonatase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPHNX_PSEP1
AccessioniPrimary (citable) accession number: A5W696
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 10, 2007
Last modified: November 2, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.