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A5W499 (UPPP_PSEP1) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:Pput_2827
OrganismPseudomonas putida (strain F1 / ATCC 700007) [Complete proteome] [HAMAP]
Taxonomic identifier351746 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 276276Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_1000062809

Regions

Transmembrane43 – 6321Helical; Potential
Transmembrane85 – 10521Helical; Potential
Transmembrane109 – 12921Helical; Potential
Transmembrane183 – 20321Helical; Potential
Transmembrane214 – 23421Helical; Potential
Transmembrane249 – 26921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
A5W499 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 93D49BB9C69797BF

FASTA27630,621
        10         20         30         40         50         60 
MDFWTAFQAI ILGVVEGLTE FLPISSTGHQ IIVADLIGFG GERAMAFNII IQLAAILAVV 

        70         80         90        100        110        120 
WEFRSKIFEV VFGLTHQPKA RRFTGNLLLA FMPAVVLGVL FADLIHEYLF NPVTVAAALV 

       130        140        150        160        170        180 
VGGVIMLWAE RRKHRVEVDH VDDMRWSHAL KIGFIQCLAM IPGTSRSGST IIGGLLFGLS 

       190        200        210        220        230        240 
RKAATEFSFF LAMPTMVGAA VYSGYKYRDL FQPGDLPVFA LGFVTSFIFA MIAVRALLKF 

       250        260        270 
IANHSYAAFA WYRIVFGLFI LATWQFGWVD WSTAHG 

« Hide

References

[1]"Complete sequence of Pseudomonas putida F1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Lykidis A., Parales R., Richardson P.
Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: F1 / ATCC 700007.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000712 Genomic DNA. Translation: ABQ78959.1.
RefSeqYP_001268143.1. NC_009512.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING351746.Pput_2827.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABQ78959; ABQ78959; Pput_2827.
GeneID5194279.
KEGGppf:Pput_2827.
PATRIC19921797. VBIPsePut56420_2883.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAMEIGTIF.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycPPUT351746:GI26-2875-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_PSEP1
AccessionPrimary (citable) accession number: A5W499
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 10, 2007
Last modified: May 14, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families