Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A5W348

- GCH4_PSEP1

UniProt

A5W348 - GCH4_PSEP1

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

GTP cyclohydrolase FolE2

Gene

folE2

Organism
Pseudomonas putida (strain F1 / ATCC 700007)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Converts GTP to 7,8-dihydroneopterin triphosphate.UniRule annotation

Catalytic activityi

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei156 – 1561May be catalytically importantUniRule annotation

GO - Molecular functioni

  1. GTP cyclohydrolase I activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 7,8-dihydroneopterin 3'-triphosphate biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciPPUT351746:GI26-2468-MONOMER.
UniPathwayiUPA00848; UER00151.

Names & Taxonomyi

Protein namesi
Recommended name:
GTP cyclohydrolase FolE2UniRule annotation (EC:3.5.4.16UniRule annotation)
Gene namesi
Name:folE2UniRule annotation
Ordered Locus Names:Pput_2420
OrganismiPseudomonas putida (strain F1 / ATCC 700007)
Taxonomic identifieri351746 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000006553: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 314314GTP cyclohydrolase FolE2PRO_0000316533Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi351746.Pput_2420.

Family & Domainsi

Sequence similaritiesi

Belongs to the GTP cyclohydrolase IV family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1469.
HOGENOMiHOG000247517.
KOiK09007.
OMAiQNLMYVE.
OrthoDBiEOG6X6RBH.

Family and domain databases

HAMAPiMF_01527_B. GTP_cyclohydrol_B.
InterProiIPR022838. GTP_cyclohydrolase_FolE2.
IPR003801. GTP_cyclohydrolase_FolE2/MptA.
IPR000048. IQ_motif_EF-hand-BS.
[Graphical view]
PfamiPF02649. GCHY-1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5W348-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSSALPDVSV TDLTHSLSPL QWVGMQGIDL PVRIEEPTYQ RELHARADVQ
60 70 80 90 100
VDLPAPHVKG IHMSRLYCLL DAWGQAAAVS PASLFALLQE MIDSHQDCGS
110 120 130 140 150
RNARLRLDFD LLVRRPALVT EGLSGWKSYS VHVLATKVGG ALNLSIEVRI
160 170 180 190 200
GYSSTCPCSA ALSRQLIEDG FLRTFKDQPL LEASAVAQWL RSNASLATPH
210 220 230 240 250
SQRSEARVRV TVPSDAPDLG LLALIDQVEG ALRTPVQTAV KRADEQAFAA
260 270 280 290 300
LNGQNLMFVE DAARRIQASL RGYRDSQVHV RHLESLHPHD ASAWSAPQAS
310
APDQQESFAT GNER
Length:314
Mass (Da):34,307
Last modified:May 5, 2009 - v2
Checksum:i4E09C943A9E59870
GO

Sequence cautioni

The sequence ABQ78558.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000712 Genomic DNA. Translation: ABQ78558.1. Different initiation.
RefSeqiWP_012052249.1. NC_009512.1.
YP_001267742.1. NC_009512.1.

Genome annotation databases

EnsemblBacteriaiABQ78558; ABQ78558; Pput_2420.
GeneIDi5195436.
KEGGippf:Pput_2420.
PATRICi19920973. VBIPsePut56420_2469.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000712 Genomic DNA. Translation: ABQ78558.1 . Different initiation.
RefSeqi WP_012052249.1. NC_009512.1.
YP_001267742.1. NC_009512.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 351746.Pput_2420.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABQ78558 ; ABQ78558 ; Pput_2420 .
GeneIDi 5195436.
KEGGi ppf:Pput_2420.
PATRICi 19920973. VBIPsePut56420_2469.

Phylogenomic databases

eggNOGi COG1469.
HOGENOMi HOG000247517.
KOi K09007.
OMAi QNLMYVE.
OrthoDBi EOG6X6RBH.

Enzyme and pathway databases

UniPathwayi UPA00848 ; UER00151 .
BioCyci PPUT351746:GI26-2468-MONOMER.

Family and domain databases

HAMAPi MF_01527_B. GTP_cyclohydrol_B.
InterProi IPR022838. GTP_cyclohydrolase_FolE2.
IPR003801. GTP_cyclohydrolase_FolE2/MptA.
IPR000048. IQ_motif_EF-hand-BS.
[Graphical view ]
Pfami PF02649. GCHY-1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: F1 / ATCC 700007.

Entry informationi

Entry nameiGCH4_PSEP1
AccessioniPrimary (citable) accession number: A5W348
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 5, 2009
Last modified: October 29, 2014
This is version 50 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3