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A5W1H1

- LFTR_PSEP1

UniProt

A5W1H1 - LFTR_PSEP1

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Protein
Leucyl/phenylalanyl-tRNA--protein transferase
Gene
aat, Pput_1828
Organism
Pseudomonas putida (strain F1 / ATCC 700007)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine By similarity.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

  1. leucyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. protein catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

BioCyciPPUT351746:GI26-1874-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferase (EC:2.3.2.6)
Alternative name(s):
L/F-transferase
Leucyltransferase
Phenyalanyltransferase
Gene namesi
Name:aat
Ordered Locus Names:Pput_1828
OrganismiPseudomonas putida (strain F1 / ATCC 700007)
Taxonomic identifieri351746 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000006553: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 226226Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation
PRO_1000045112Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi351746.Pput_1828.

Structurei

3D structure databases

ProteinModelPortaliA5W1H1.

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.

Phylogenomic databases

eggNOGiCOG2360.
HOGENOMiHOG000102325.
KOiK00684.
OMAiWSPDPRG.
OrthoDBiEOG6WX4R3.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.

Sequencei

Sequence statusi: Complete.

A5W1H1-1 [UniParc]FASTAAdd to Basket

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MLTWLTRDSL TFPPLEKALH DPNGLLAAGG DLSPERLVQA YRHGCFPWYQ    50
DGQPILWWSP DPRTVLLPDQ LHVSRSLAKL MRQGRYQVSF DTDFPAVIAA 100
CAAPRDYADG TWITDTMRNA YCELHRRGIA HSVEVRQDGE LVGGLYGLAM 150
GQLFFGESMF SRADNASKVG FVTLVNHLRD AGFVLIDCQM PTNHLHSLGA 200
HAISRAEFAS YLARHLDQPN SASWVA 226
Length:226
Mass (Da):25,194
Last modified:July 10, 2007 - v1
Checksum:i260CB53304D496D7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000712 Genomic DNA. Translation: ABQ77981.1.
RefSeqiYP_001267165.1. NC_009512.1.

Genome annotation databases

EnsemblBacteriaiABQ77981; ABQ77981; Pput_1828.
GeneIDi5195042.
KEGGippf:Pput_1828.
PATRICi19919752. VBIPsePut56420_1861.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000712 Genomic DNA. Translation: ABQ77981.1 .
RefSeqi YP_001267165.1. NC_009512.1.

3D structure databases

ProteinModelPortali A5W1H1.
ModBasei Search...

Protein-protein interaction databases

STRINGi 351746.Pput_1828.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABQ77981 ; ABQ77981 ; Pput_1828 .
GeneIDi 5195042.
KEGGi ppf:Pput_1828.
PATRICi 19919752. VBIPsePut56420_1861.

Phylogenomic databases

eggNOGi COG2360.
HOGENOMi HOG000102325.
KOi K00684.
OMAi WSPDPRG.
OrthoDBi EOG6WX4R3.

Enzyme and pathway databases

BioCyci PPUT351746:GI26-1874-MONOMER.

Family and domain databases

HAMAPi MF_00688. Leu_Phe_trans.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view ]
Pfami PF03588. Leu_Phe_trans. 1 hit.
[Graphical view ]
SUPFAMi SSF55729. SSF55729. 1 hit.
TIGRFAMsi TIGR00667. aat. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: F1 / ATCC 700007.

Entry informationi

Entry nameiLFTR_PSEP1
AccessioniPrimary (citable) accession number: A5W1H1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 10, 2007
Last modified: May 14, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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