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A5W1G5

- A5W1G5_PSEP1

UniProt

A5W1G5 - A5W1G5_PSEP1

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Protein

Isocitrate dehydrogenase [NADP]

Gene

Pput_1822

Organism
Pseudomonas putida (strain F1 / ATCC 700007)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Binds 1 magnesium or manganese ion per subunit.UniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciPPUT351746:GI26-1868-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Ordered Locus Names:Pput_1822Imported
OrganismiPseudomonas putida (strain F1 / ATCC 700007)Imported
Taxonomic identifieri351746 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000006553: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi351746.Pput_1822.

Structurei

3D structure databases

ProteinModelPortaliA5W1G5.
SMRiA5W1G5. Positions 5-418.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0538.
HOGENOMiHOG000021113.
KOiK00031.
OMAiCLRPIRY.
OrthoDBiEOG6SNDTP.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5W1G5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGYQKIKVPT DGTKITVNAD HSLNVPDHPI IPYIEGDGIG VDVSPVMIKV
60 70 80 90 100
VDAAVHKAYG GKRKIAWMEV YAGEKATQVY DQDTWLPQET LDAVRDYVVS
110 120 130 140 150
IKGPLTTPVG GGIRSLNVAL RQQLDLYVCL RPVLWFQGVP SPVKKPGDVD
160 170 180 190 200
MVIFRENSED IYAGIEWKAG SPEANKVIKF LKEEMGVTKI RFDQDCGIGV
210 220 230 240 250
KPVSKEGTKR LVRKALQYVV DNDRESLTLV HKGNIMKFTE GAFKDWGYEV
260 270 280 290 300
ARDEFGAELL DGGPWMKFKN PKTGREVIVK DAIADAMLQQ ILLRPAEYDV
310 320 330 340 350
IATLNLNGDY LSDALAAEVG GIGIAPGANL SDTVAMFEAT HGTAPKYAGQ
360 370 380 390 400
DKVNPGSVIL SAEMMLRHMG WTEAADLIIK GTNGAIAAKT VTYDFERLME
410
GAKLVSSSGF GDEMIKHM
Length:418
Mass (Da):45,705
Last modified:July 10, 2007 - v1
Checksum:i81779C112CE46E4C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000712 Genomic DNA. Translation: ABQ77975.1.
RefSeqiYP_001267159.1. NC_009512.1.

Genome annotation databases

EnsemblBacteriaiABQ77975; ABQ77975; Pput_1822.
GeneIDi5194350.
KEGGippf:Pput_1822.
PATRICi19919740. VBIPsePut56420_1855.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000712 Genomic DNA. Translation: ABQ77975.1 .
RefSeqi YP_001267159.1. NC_009512.1.

3D structure databases

ProteinModelPortali A5W1G5.
SMRi A5W1G5. Positions 5-418.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 351746.Pput_1822.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABQ77975 ; ABQ77975 ; Pput_1822 .
GeneIDi 5194350.
KEGGi ppf:Pput_1822.
PATRICi 19919740. VBIPsePut56420_1855.

Phylogenomic databases

eggNOGi COG0538.
HOGENOMi HOG000021113.
KOi K00031.
OMAi CLRPIRY.
OrthoDBi EOG6SNDTP.

Enzyme and pathway databases

BioCyci PPUT351746:GI26-1868-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 1 hit.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: F1 / ATCC 700007Imported.

Entry informationi

Entry nameiA5W1G5_PSEP1
AccessioniPrimary (citable) accession number: A5W1G5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: October 29, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3