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A5W1G4

- A5W1G4_PSEP1

UniProt

A5W1G4 - A5W1G4_PSEP1

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Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene
Pput_1821
Organism
Pseudomonas putida (strain F1 / ATCC 700007)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei172 – 1721Substrate By similarityUniRule annotation
Sitei282 – 2821Critical for catalysis By similarityUniRule annotation
Metal bindingi377 – 3771Magnesium or manganese By similarityUniRule annotation
Sitei447 – 4471Critical for catalysis By similarityUniRule annotation
Binding sitei574 – 5741Substrate By similarityUniRule annotation
Metal bindingi575 – 5751Magnesium or manganese By similarityUniRule annotation
Metal bindingi579 – 5791Magnesium or manganese By similarityUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciPPUT351746:GI26-1867-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:Pput_1821Imported
OrganismiPseudomonas putida (strain F1 / ATCC 700007)Imported
Taxonomic identifieri351746 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000006553: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi351746.Pput_1821.

Structurei

3D structure databases

ProteinModelPortaliA5W1G4.
SMRiA5W1G4. Positions 32-767.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni159 – 1668Substrate binding By similarityUniRule annotation

Phylogenomic databases

eggNOGiCOG2838.
HOGENOMiHOG000240860.
KOiK00031.
OMAiEEQRIGD.
OrthoDBiEOG6DVJPP.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

A5W1G4-1 [UniParc]FASTAAdd to Basket

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MALPGRCAYP AHHETRARSA HRELTRMPTR SKIIYTFTDE APALATYSLL    50
PIIEAFTASA DIAVETRDIS LAGRILAAFP EQLGAEKQVG DHLAELGQLA 100
TTPEANIIKL PNISASVPQL KAAIKELQGK GFNIPDYADE PATAEEKESR 150
ARYDRIKGSA VNPVLREGNS DRRAPLSVKN YARKHPHKMG AWAADSKSHV 200
AHMTQGDFYG SEKAALIEAD DSLRIELVAK DGSTTVLKEK TAVKAAEVID 250
CATMSRKALK AFIAEQIADA KAAGVLLSVH LKATMMKVSD PIMFGVIVEE 300
FYNDVLTKHA AALAEVGFNA NNGIGDLYAR IKDLPADKQA EIEADIQALY 350
AERPALAMVN SDKGITNLHV PSDVIVDASM PAMIRDSGKM WNTAGELQDA 400
KAVIPDRCYA GIYQATIEDC KVNGAFDPTT MGSVPNVGLM AQKAEEYGSH 450
DKTFQVKADG VVRVVDGKGN VVLEQNVEAG DIFRMCQTKD APIQDWVKLA 500
VNRARLSNTP AVFWLDPARA HDGVMIEKVQ KYLKDHDTTG LDIRILAPVD 550
AIKFSLARIR EGKDTISVTG NVLRDYLTDL FPIMELGTSA KMLSIVPLMS 600
GGGLFETGAG GSAPKHVQQL VEENFLRWDS LGEFLALAAS LEHLGNTYDN 650
PRAKVLANTL DQATGKFLDT NKSPSRKVGG IDNRGSHFYL TLYWAEALAA 700
QTDDAALQAR FAPLAKTLAE NEATIVAELN AVQGKPADIG GYYAPDAELT 750
AKVMRPSQTL NSAIAAL 767
Length:767
Mass (Da):82,873
Last modified:July 10, 2007 - v1
Checksum:iD2CDC55367A77E4A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000712 Genomic DNA. Translation: ABQ77974.1.
RefSeqiWP_012051823.1. NC_009512.1.
YP_001267158.1. NC_009512.1.

Genome annotation databases

EnsemblBacteriaiABQ77974; ABQ77974; Pput_1821.
GeneIDi5194090.
KEGGippf:Pput_1821.
PATRICi19919738. VBIPsePut56420_1854.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000712 Genomic DNA. Translation: ABQ77974.1 .
RefSeqi WP_012051823.1. NC_009512.1.
YP_001267158.1. NC_009512.1.

3D structure databases

ProteinModelPortali A5W1G4.
SMRi A5W1G4. Positions 32-767.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 351746.Pput_1821.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABQ77974 ; ABQ77974 ; Pput_1821 .
GeneIDi 5194090.
KEGGi ppf:Pput_1821.
PATRICi 19919738. VBIPsePut56420_1854.

Phylogenomic databases

eggNOGi COG2838.
HOGENOMi HOG000240860.
KOi K00031.
OMAi EEQRIGD.
OrthoDBi EOG6DVJPP.

Enzyme and pathway databases

BioCyci PPUT351746:GI26-1867-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: F1 / ATCC 700007.

Entry informationi

Entry nameiA5W1G4_PSEP1
AccessioniPrimary (citable) accession number: A5W1G4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: September 3, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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