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A5W1G4

- A5W1G4_PSEP1

UniProt

A5W1G4 - A5W1G4_PSEP1

Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Pput_1821

Organism
Pseudomonas putida (strain F1 / ATCC 700007)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (10 Jul 2007)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei172 – 1721SubstrateUniRule annotation
    Sitei282 – 2821Critical for catalysisUniRule annotation
    Metal bindingi377 – 3771Magnesium or manganeseUniRule annotation
    Sitei447 – 4471Critical for catalysisUniRule annotation
    Binding sitei574 – 5741Substrate
    Metal bindingi575 – 5751Magnesium or manganeseUniRule annotation
    Metal bindingi579 – 5791Magnesium or manganeseUniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciPPUT351746:GI26-1867-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
    Gene namesi
    Ordered Locus Names:Pput_1821Imported
    OrganismiPseudomonas putida (strain F1 / ATCC 700007)Imported
    Taxonomic identifieri351746 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000006553: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi351746.Pput_1821.

    Structurei

    3D structure databases

    ProteinModelPortaliA5W1G4.
    SMRiA5W1G4. Positions 32-767.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni159 – 1668Substrate binding

    Phylogenomic databases

    eggNOGiCOG2838.
    HOGENOMiHOG000240860.
    KOiK00031.
    OMAiEEQRIGD.
    OrthoDBiEOG6DVJPP.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A5W1G4-1 [UniParc]FASTAAdd to Basket

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    MALPGRCAYP AHHETRARSA HRELTRMPTR SKIIYTFTDE APALATYSLL    50
    PIIEAFTASA DIAVETRDIS LAGRILAAFP EQLGAEKQVG DHLAELGQLA 100
    TTPEANIIKL PNISASVPQL KAAIKELQGK GFNIPDYADE PATAEEKESR 150
    ARYDRIKGSA VNPVLREGNS DRRAPLSVKN YARKHPHKMG AWAADSKSHV 200
    AHMTQGDFYG SEKAALIEAD DSLRIELVAK DGSTTVLKEK TAVKAAEVID 250
    CATMSRKALK AFIAEQIADA KAAGVLLSVH LKATMMKVSD PIMFGVIVEE 300
    FYNDVLTKHA AALAEVGFNA NNGIGDLYAR IKDLPADKQA EIEADIQALY 350
    AERPALAMVN SDKGITNLHV PSDVIVDASM PAMIRDSGKM WNTAGELQDA 400
    KAVIPDRCYA GIYQATIEDC KVNGAFDPTT MGSVPNVGLM AQKAEEYGSH 450
    DKTFQVKADG VVRVVDGKGN VVLEQNVEAG DIFRMCQTKD APIQDWVKLA 500
    VNRARLSNTP AVFWLDPARA HDGVMIEKVQ KYLKDHDTTG LDIRILAPVD 550
    AIKFSLARIR EGKDTISVTG NVLRDYLTDL FPIMELGTSA KMLSIVPLMS 600
    GGGLFETGAG GSAPKHVQQL VEENFLRWDS LGEFLALAAS LEHLGNTYDN 650
    PRAKVLANTL DQATGKFLDT NKSPSRKVGG IDNRGSHFYL TLYWAEALAA 700
    QTDDAALQAR FAPLAKTLAE NEATIVAELN AVQGKPADIG GYYAPDAELT 750
    AKVMRPSQTL NSAIAAL 767
    Length:767
    Mass (Da):82,873
    Last modified:July 10, 2007 - v1
    Checksum:iD2CDC55367A77E4A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000712 Genomic DNA. Translation: ABQ77974.1.
    RefSeqiWP_012051823.1. NC_009512.1.
    YP_001267158.1. NC_009512.1.

    Genome annotation databases

    EnsemblBacteriaiABQ77974; ABQ77974; Pput_1821.
    GeneIDi5194090.
    KEGGippf:Pput_1821.
    PATRICi19919738. VBIPsePut56420_1854.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000712 Genomic DNA. Translation: ABQ77974.1 .
    RefSeqi WP_012051823.1. NC_009512.1.
    YP_001267158.1. NC_009512.1.

    3D structure databases

    ProteinModelPortali A5W1G4.
    SMRi A5W1G4. Positions 32-767.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 351746.Pput_1821.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABQ77974 ; ABQ77974 ; Pput_1821 .
    GeneIDi 5194090.
    KEGGi ppf:Pput_1821.
    PATRICi 19919738. VBIPsePut56420_1854.

    Phylogenomic databases

    eggNOGi COG2838.
    HOGENOMi HOG000240860.
    KOi K00031.
    OMAi EEQRIGD.
    OrthoDBi EOG6DVJPP.

    Enzyme and pathway databases

    BioCyci PPUT351746:GI26-1867-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: F1 / ATCC 700007Imported.

    Entry informationi

    Entry nameiA5W1G4_PSEP1
    AccessioniPrimary (citable) accession number: A5W1G4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 10, 2007
    Last sequence update: July 10, 2007
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3