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Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Pput_1821

Organism
Pseudomonas putida (strain F1 / ATCC 700007)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Cofactori

Mg2+UniRule annotation, Mn2+UniRule annotationNote: Binds 1 Mg(2+) or Mn2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei172 – 1721SubstrateUniRule annotation
Sitei282 – 2821Critical for catalysisUniRule annotation
Metal bindingi377 – 3771Magnesium or manganeseUniRule annotation
Sitei447 – 4471Critical for catalysisUniRule annotation
Binding sitei574 – 5741SubstrateUniRule annotation
Metal bindingi575 – 5751Magnesium or manganeseUniRule annotation
Metal bindingi579 – 5791Magnesium or manganeseUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciPPUT351746:GI26-1867-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:Pput_1821Imported
OrganismiPseudomonas putida (strain F1 / ATCC 700007)Imported
Taxonomic identifieri351746 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000006553 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi351746.Pput_1821.

Structurei

3D structure databases

ProteinModelPortaliA5W1G4.
SMRiA5W1G4. Positions 32-767.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni159 – 1668Substrate bindingUniRule annotation

Phylogenomic databases

eggNOGiCOG2838.
HOGENOMiHOG000240860.
KOiK00031.
OMAiRDSGKMW.
OrthoDBiEOG6DVJPP.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

A5W1G4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALPGRCAYP AHHETRARSA HRELTRMPTR SKIIYTFTDE APALATYSLL
60 70 80 90 100
PIIEAFTASA DIAVETRDIS LAGRILAAFP EQLGAEKQVG DHLAELGQLA
110 120 130 140 150
TTPEANIIKL PNISASVPQL KAAIKELQGK GFNIPDYADE PATAEEKESR
160 170 180 190 200
ARYDRIKGSA VNPVLREGNS DRRAPLSVKN YARKHPHKMG AWAADSKSHV
210 220 230 240 250
AHMTQGDFYG SEKAALIEAD DSLRIELVAK DGSTTVLKEK TAVKAAEVID
260 270 280 290 300
CATMSRKALK AFIAEQIADA KAAGVLLSVH LKATMMKVSD PIMFGVIVEE
310 320 330 340 350
FYNDVLTKHA AALAEVGFNA NNGIGDLYAR IKDLPADKQA EIEADIQALY
360 370 380 390 400
AERPALAMVN SDKGITNLHV PSDVIVDASM PAMIRDSGKM WNTAGELQDA
410 420 430 440 450
KAVIPDRCYA GIYQATIEDC KVNGAFDPTT MGSVPNVGLM AQKAEEYGSH
460 470 480 490 500
DKTFQVKADG VVRVVDGKGN VVLEQNVEAG DIFRMCQTKD APIQDWVKLA
510 520 530 540 550
VNRARLSNTP AVFWLDPARA HDGVMIEKVQ KYLKDHDTTG LDIRILAPVD
560 570 580 590 600
AIKFSLARIR EGKDTISVTG NVLRDYLTDL FPIMELGTSA KMLSIVPLMS
610 620 630 640 650
GGGLFETGAG GSAPKHVQQL VEENFLRWDS LGEFLALAAS LEHLGNTYDN
660 670 680 690 700
PRAKVLANTL DQATGKFLDT NKSPSRKVGG IDNRGSHFYL TLYWAEALAA
710 720 730 740 750
QTDDAALQAR FAPLAKTLAE NEATIVAELN AVQGKPADIG GYYAPDAELT
760
AKVMRPSQTL NSAIAAL
Length:767
Mass (Da):82,873
Last modified:July 10, 2007 - v1
Checksum:iD2CDC55367A77E4A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000712 Genomic DNA. Translation: ABQ77974.1.

Genome annotation databases

EnsemblBacteriaiABQ77974; ABQ77974; Pput_1821.
KEGGippf:Pput_1821.
PATRICi19919738. VBIPsePut56420_1854.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000712 Genomic DNA. Translation: ABQ77974.1.

3D structure databases

ProteinModelPortaliA5W1G4.
SMRiA5W1G4. Positions 32-767.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi351746.Pput_1821.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ77974; ABQ77974; Pput_1821.
KEGGippf:Pput_1821.
PATRICi19919738. VBIPsePut56420_1854.

Phylogenomic databases

eggNOGiCOG2838.
HOGENOMiHOG000240860.
KOiK00031.
OMAiRDSGKMW.
OrthoDBiEOG6DVJPP.

Enzyme and pathway databases

BioCyciPPUT351746:GI26-1867-MONOMER.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: F1 / ATCC 700007Imported.

Entry informationi

Entry nameiA5W1G4_PSEP1
AccessioniPrimary (citable) accession number: A5W1G4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: July 22, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.