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Protein

C4-dicarboxylate transport protein

Gene

dctA

Organism
Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Symport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
C4-dicarboxylate transport proteinUniRule annotation
Gene namesi
Name:dctAUniRule annotation
Ordered Locus Names:Pput_1218
OrganismiPseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)
Taxonomic identifieri351746 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000006553 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei15 – 35HelicalUniRule annotationAdd BLAST21
Transmembranei46 – 66HelicalUniRule annotationAdd BLAST21
Transmembranei78 – 98HelicalUniRule annotationAdd BLAST21
Transmembranei146 – 166HelicalUniRule annotationAdd BLAST21
Transmembranei190 – 210HelicalUniRule annotationAdd BLAST21
Transmembranei224 – 244HelicalUniRule annotationAdd BLAST21
Transmembranei291 – 311HelicalUniRule annotationAdd BLAST21
Transmembranei332 – 352HelicalUniRule annotationAdd BLAST21
Transmembranei354 – 374HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000674551 – 440C4-dicarboxylate transport proteinAdd BLAST440

Interactioni

Protein-protein interaction databases

STRINGi351746.Pput_1218.

Structurei

3D structure databases

ProteinModelPortaliA5VZR9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CK2. Bacteria.
COG1301. LUCA.
HOGENOMiHOG000208775.
KOiK11103.
OMAiIKMERLG.

Family and domain databases

Gene3Di1.10.3860.10. 1 hit.
HAMAPiMF_01300. C4_dicarb_transport. 1 hit.
InterProiIPR023954. C4_dicarb_transport.
IPR001991. Na-dicarboxylate_symporter.
IPR018107. Na-dicarboxylate_symporter_CS.
[Graphical view]
PANTHERiPTHR11958. PTHR11958. 1 hit.
PfamiPF00375. SDF. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 1 hit.
PROSITEiPS00713. NA_DICARBOXYL_SYMP_1. 1 hit.
PS00714. NA_DICARBOXYL_SYMP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5VZR9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTRQPLYKS LYVQVLVAIT IGILLGHYYP ETGVALKPLG DGFVKLIKMV
60 70 80 90 100
IAPIIFCTVV SGIAGMQSMK SVGKTGGYAL LYFEIVSTIA LIIGLVVVNV
110 120 130 140 150
VKPGAGMHID VSTLNASSVA AYAAAGAQQT TVGFLLNVIP NTVVGAFANG
160 170 180 190 200
DILQVLMFSV LFGFALHRLG SYGKPVLDMI DRFAHVMFNI INMIMKLAPI
210 220 230 240 250
GAFGAMAFTI GQYGVGSLVQ LGYLMACFYI TCLLFVLVVL GGICRAHGFS
260 270 280 290 300
VIKLIRYIRE ELLIVLGTSS SESALPRMLA KMERLGAKKS VVGLVIPTGY
310 320 330 340 350
SFNLDGTSIY LTMAAVFIAQ ATDTTMDITH QITLLLVLLV ASKGAAGVTG
360 370 380 390 400
SGFIVLAATL SAVGHLPVAG LALILGIDRF MSEARALTNL VGNAVATVVV
410 420 430 440
AKWVKEMDND KLASELASGG APLVDTRPTD DLGVAEGPAR
Length:440
Mass (Da):46,240
Last modified:July 10, 2007 - v1
Checksum:i449774117CE4A795
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000712 Genomic DNA. Translation: ABQ77379.1.
RefSeqiWP_003254811.1. NC_009512.1.

Genome annotation databases

EnsemblBacteriaiABQ77379; ABQ77379; Pput_1218.
KEGGippf:Pput_1218.
PATRICi19918475. VBIPsePut56420_1232.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000712 Genomic DNA. Translation: ABQ77379.1.
RefSeqiWP_003254811.1. NC_009512.1.

3D structure databases

ProteinModelPortaliA5VZR9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi351746.Pput_1218.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ77379; ABQ77379; Pput_1218.
KEGGippf:Pput_1218.
PATRICi19918475. VBIPsePut56420_1232.

Phylogenomic databases

eggNOGiENOG4105CK2. Bacteria.
COG1301. LUCA.
HOGENOMiHOG000208775.
KOiK11103.
OMAiIKMERLG.

Family and domain databases

Gene3Di1.10.3860.10. 1 hit.
HAMAPiMF_01300. C4_dicarb_transport. 1 hit.
InterProiIPR023954. C4_dicarb_transport.
IPR001991. Na-dicarboxylate_symporter.
IPR018107. Na-dicarboxylate_symporter_CS.
[Graphical view]
PANTHERiPTHR11958. PTHR11958. 1 hit.
PfamiPF00375. SDF. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 1 hit.
PROSITEiPS00713. NA_DICARBOXYL_SYMP_1. 1 hit.
PS00714. NA_DICARBOXYL_SYMP_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDCTA_PSEP1
AccessioniPrimary (citable) accession number: A5VZR9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 10, 2007
Last modified: November 2, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.