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Protein

Glutamate decarboxylase

Gene

BOV_A0309

Organism
Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciBOVI444178:GH2V-2403-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:BOV_A0309Imported
OrganismiBrucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)Imported
Taxonomic identifieri444178 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000006383 Componenti: Chromosome II

Interactioni

Protein-protein interaction databases

STRINGi444178.BOV_A0309.

Structurei

3D structure databases

ProteinModelPortaliA5VU56.
SMRiA5VU56. Positions 21-440.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiDPDLVWD.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR021115. Pyridoxal-P_BS.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5VU56-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPASVFGTE ALQEIAASRG FREKEMQANA VYQIIHDELF LDGNARQNLA
60 70 80 90 100
TFCQTWDDDY VHKLMDLSIN KNWIDKEEYP QSAAIDLRCV NMVADLWNAP
110 120 130 140 150
KFADNATGTN TIGSSEACML GGMAMKWRWR KKMQEMGKPT DKPNFVCGPV
160 170 180 190 200
QVCWHKFARY WDVEIREIPM EPGRLFMGPE QMLEAVDENT IGVVPTFGVT
210 220 230 240 250
YTGNYEFPEP LQDALDKLQK TKGLDIDIHV DAASGGFLAP FCAPDIPWDF
260 270 280 290 300
RLPRVKSISA SGHKYGLAPL GCGWVVWRDK EALPEELIFN VDYLGGQVGT
310 320 330 340 350
FAINFSRPAG QVISQYYEFM RLGREGYTKV QQAAYRVAQY IAREIEPLGP
360 370 380 390 400
YEFICAGEEK GGIPAVCFRI REGEDPGYSL YDLSERLRLT GWQVPAFALS
410 420 430 440 450
GKASDITVMR VMCRRGFEMD LAALFIRDFK AGIEFFKSHP SPKITPSMGT

GFHHT
Length:455
Mass (Da):51,265
Last modified:July 9, 2007 - v1
Checksum:i504B363BDE5C444B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000709 Genomic DNA. Translation: ABQ62050.1.
RefSeqiYP_001257361.1. NC_009504.1.

Genome annotation databases

EnsemblBacteriaiABQ62050; ABQ62050; BOV_A0309.
KEGGibov:BOV_A0309.
PATRICi17857814. VBIBruOvi136990_0358.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000709 Genomic DNA. Translation: ABQ62050.1.
RefSeqiYP_001257361.1. NC_009504.1.

3D structure databases

ProteinModelPortaliA5VU56.
SMRiA5VU56. Positions 21-440.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi444178.BOV_A0309.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ62050; ABQ62050; BOV_A0309.
KEGGibov:BOV_A0309.
PATRICi17857814. VBIBruOvi136990_0358.

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiDPDLVWD.
OrthoDBiEOG6TFCPW.

Enzyme and pathway databases

BioCyciBOVI444178:GH2V-2403-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR021115. Pyridoxal-P_BS.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25840 / 63/290 / NCTC 10512Imported.

Entry informationi

Entry nameiA5VU56_BRUO2
AccessioniPrimary (citable) accession number: A5VU56
Entry historyi
Integrated into UniProtKB/TrEMBL: July 9, 2007
Last sequence update: July 9, 2007
Last modified: March 31, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.