A5VS47 (GLMM_BRUO2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	BOV_1634

Organism

Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512) [Complete proteome] [HAMAP]

Taxonomic identifier

444178 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	451 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 451	451	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000305634
Sites
	Active site	102	1	Phosphoserine intermediate By similarity
	Metal binding	102	1	Magnesium; via phosphate group By similarity
	Metal binding	243	1	Magnesium By similarity
	Metal binding	245	1	Magnesium By similarity
	Metal binding	247	1	Magnesium By similarity
Amino acid modifications
	Modified residue	102	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A5VS47 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: ADA445AE3D805CD5	FASTA	451	48,569
	10 20 30 40 50 60 MTRKFFGTDG IRGQANSFPM TPEIAMKVGM AVGYIFRRKG QASRVVIGKD TRRSGYMLEN 70 80 90 100 110 120 ALVAGFTAAG MDVFLLGPIP TPAVAMLCRS LRADIGVMIS ASHNPFYDNG IKLFGPDGFK 130 140 150 160 170 180 LSDQIELQIE AMIEGDMTPF LASHGDVGRA KRVDGDIYRY IEFAKRTLPR NISLNGLRVV 190 200 210 220 230 240 VDCANGAGYK VAPAALWELG AEVITINNEP NGININEDCG STHPIGLMKK VHEVRADVGI 250 260 270 280 290 300 ALDGDADRVL LVDENGTVID GDQLMAVIAE SWAASNRLEG GGIVATVMSN LGLERFLADR 310 320 330 340 350 360 NLTLARTKVG DRYVVEHMRE HGFNVGGEQS GHIVLSDFAT TGDGLISALQ ILAVAQEQNK 370 380 390 400 410 420 PISDVCRKFQ PVPQLLKNVR TTGGKPLENK RVKSAIDEAK ERLGGQGRLV IRPSGTEPLI 430 440 450 RVMAEGDDRG LVEKVVNDII DVISSESSAA A

References

[1]	Paulsen I. Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25840 / 63/290 / NCTC 10512.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000708 Genomic DNA. Translation: ABQ60403.1.
RefSeq	YP_001259544.1. NC_009505.1.
3D structure databases
ProteinModelPortal	A5VS47.
ModBase	Search...
Protein-protein interaction databases
STRING	A5VS47.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5202053.
GenomeReviews	Gene locus BOV_1634 in contig CP000708_GR.
KEGG	bov:BOV_1634.
PATRIC	17863316. VBIBruOvi136990_3041.
TIGR	BOV_1634.
Phylogenomic databases
HOGENOM	HBG644964.
OMA	PLEDIQV.
ProtClustDB	PRK14315.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 2 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_BRUO2

Accession

Primary (citable) accession number: A5VS47

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 2, 2007
Last sequence update:	July 10, 2007
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program