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A5VR08

- EFTU_BRUO2

UniProt

A5VR08 - EFTU_BRUO2

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Protein

Elongation factor Tu

Gene

tuf1

more
Organism
Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi76 – 805GTPUniRule annotation
Nucleotide bindingi131 – 1344GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBOVI444178:GH2V-1197-MONOMER.
BOVI444178:GH2V-1212-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tuf1UniRule annotation
Ordered Locus Names:BOV_1198
AND
Name:tuf2UniRule annotation
Ordered Locus Names:BOV_1213
OrganismiBrucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)
Taxonomic identifieri444178 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000006383: Chromosome I

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 391391Elongation factor TuPRO_0000337332Add
BLAST

Proteomic databases

PRIDEiA5VR08.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi444178.BOV_1213.

Structurei

3D structure databases

ProteinModelPortaliA5VR08.
SMRiA5VR08. Positions 2-390.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 201192tr-type GAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni19 – 268G1By similarity
Regioni55 – 595G2By similarity
Regioni76 – 794G3By similarity
Regioni131 – 1344G4By similarity
Regioni169 – 1713G5By similarity

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0050.
HOGENOMiHOG000229290.
KOiK02358.
OMAiGTEMCMP.
OrthoDBiEOG6R5C6X.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5VR08-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAKSKFERTK PHVNIGTIGH VDHGKTSLTA AITKFFGEFK AYDQIDAAPE
60 70 80 90 100
ERARGITIST AHVEYETANR HYAHVDCPGH ADYVKNMITG AAQMDGAILV
110 120 130 140 150
VSAADGPMPQ TREHILLARQ VGVPAIVVFL NKCDQVDDAE LLELVELEVR
160 170 180 190 200
ELLSKYEFPG DEIPIIKGSA LAALEDSSKE LGEDAIRNLM DAVDSYIPTP
210 220 230 240 250
ERPIDQPFLM PIEDVFSISG RGTVVTGRVE RGIVKVGEEV EIVGIKATTK
260 270 280 290 300
TTVTGVEMFR KLLDQGQAGD NIGALIRGVG REDVERGQVL CKPGSVKPHT
310 320 330 340 350
KFKAEAYILT KDEGGRHTPF FTNYRPQFYF RTTDVTGVVT LPAGTEMVMP
360 370 380 390
GDNVAMDVTL IVPIAMEEKL RFAIREGGRT VGAGIVSSII E
Length:391
Mass (Da):42,605
Last modified:July 10, 2007 - v1
Checksum:iED4CDF37183A900E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000708 Genomic DNA. Translation: ABQ60947.1.
CP000708 Genomic DNA. Translation: ABQ61477.1.
RefSeqiYP_001259155.1. NC_009505.1.
YP_001259169.1. NC_009505.1.

Genome annotation databases

EnsemblBacteriaiABQ60947; ABQ60947; BOV_1213.
ABQ61477; ABQ61477; BOV_1198.
GeneIDi5202025.
5202557.
KEGGibov:BOV_1198.
bov:BOV_1213.
PATRICi17862334. VBIBruOvi136990_2570.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000708 Genomic DNA. Translation: ABQ60947.1 .
CP000708 Genomic DNA. Translation: ABQ61477.1 .
RefSeqi YP_001259155.1. NC_009505.1.
YP_001259169.1. NC_009505.1.

3D structure databases

ProteinModelPortali A5VR08.
SMRi A5VR08. Positions 2-390.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 444178.BOV_1213.

Proteomic databases

PRIDEi A5VR08.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABQ60947 ; ABQ60947 ; BOV_1213 .
ABQ61477 ; ABQ61477 ; BOV_1198 .
GeneIDi 5202025.
5202557.
KEGGi bov:BOV_1198.
bov:BOV_1213.
PATRICi 17862334. VBIBruOvi136990_2570.

Phylogenomic databases

eggNOGi COG0050.
HOGENOMi HOG000229290.
KOi K02358.
OMAi GTEMCMP.
OrthoDBi EOG6R5C6X.

Enzyme and pathway databases

BioCyci BOVI444178:GH2V-1197-MONOMER.
BOVI444178:GH2V-1212-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00118_B. EF_Tu_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Paulsen I.
    Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25840 / 63/290 / NCTC 10512.

Entry informationi

Entry nameiEFTU_BRUO2
AccessioniPrimary (citable) accession number: A5VR08
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 10, 2007
Last modified: October 29, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3