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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Lactobacillus reuteri (strain DSM 20016)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei142GTPUniRule annotation1
Binding sitei146GTPUniRule annotation1
Binding sitei190GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi24 – 28GTPUniRule annotation5
Nucleotide bindingi111 – 113GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:Lreu_0593Imported
OrganismiLactobacillus reuteri (strain DSM 20016)Imported
Taxonomic identifieri557436 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000001991 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA5VJ36
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 208TubulinInterPro annotationAdd BLAST193
Domaini210 – 327Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

A5VJ36-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNETFANDN QFAEAQIKVI GVGGAGGNAV NRMITEKVQG VDFIVANTDL
60 70 80 90 100
QALNNSQATT KIRLGPKLTK GLGAGSNPEV GEKAAQESEE QIKKALEGAD
110 120 130 140 150
MVFITAGMGG GTGTGAAPVV AKLAKDSGAL TVGVVTRPFS FEGPRRARYA
160 170 180 190 200
AEGLEKLKSN VDTLIIVANN RLLEMIDKKT PMMEAFKEAD NVLRQGVQGI
210 220 230 240 250
SDLIVTPGYI NLDFADIKTL MSNQGSALMG VGASTGENRA TEATKKAISS
260 270 280 290 300
PLLEVSIDGA QHVLMDITGG KDLSMFEAQE ASDVIKQAAG TNVDISFGMS
310 320 330 340 350
LNESMGDEVR VTVIATGIDK KKKIQQQKPA EKEAPRVTRS IPQEEQPVEQ
360 370 380 390 400
PKQRDPFDGW NDPTADTSNQ SRNSDNEFSH VTKPEFNVFN DDAANTDDND
410
DTNLSTPPFF KNRRK
Length:415
Mass (Da):44,451
Last modified:July 10, 2007 - v1
Checksum:i7346783A772B53E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000705 Genomic DNA Translation: ABQ82860.1
RefSeqiWP_003666768.1, NZ_AZDD01000002.1

Genome annotation databases

EnsemblBacteriaiABQ82860; ABQ82860; Lreu_0593
GeneIDi5189582
KEGGilre:Lreu_0593
PATRICifig|557436.17.peg.665

Similar proteinsi

Entry informationi

Entry nameiA5VJ36_LACRD
AccessioniPrimary (citable) accession number: A5VJ36
Entry historyiIntegrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: March 28, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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