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A5VIP5 (A5VIP5_LACRD) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length191 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124 RuleBase RU000544 SAAS SAAS020634

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124 SAAS SAAS020633

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124 SAAS SAAS020633.

Sequence similarities

Belongs to the thymidine kinase family. HAMAP-Rule MF_00124

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding9 – 168ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding85 – 884ATP By similarity HAMAP-Rule MF_00124

Sites

Active site861Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1431Zinc By similarity HAMAP-Rule MF_00124
Metal binding1461Zinc By similarity HAMAP-Rule MF_00124
Metal binding1801Zinc By similarity HAMAP-Rule MF_00124
Metal binding1831Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
A5VIP5 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 56A1541E23FACF45

FASTA19122,171
        10         20         30         40         50         60 
MAQLFFKYGA MNSGKSIDIL KVAHNYEEQG KPVVLMTSGV DDRSGRGIIA SRIGLERKVK 

        70         80         90        100        110        120 
PIMDDTNIYD YVNKMDRKIY CVLIDEAQFL KKEHVLQLIK IVDELNIPVM AFGLKNDFRN 

       130        140        150        160        170        180 
ELFEGSKYLL IYADKIEEMK TICWFCPHKA TMNLRIHNGK PVYEGEQVQI GGNESYYPVC 

       190 
RKHYFHPQLK Q 

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References

[1]"The evolution of host specialization in the vertebrate gut symbiont Lactobacillus reuteri."
Frese S.A., Benson A.K., Tannock G.W., Loach D.M., Kim J., Zhang M., Oh P.L., Heng N.C., Patil P.B., Juge N., Mackenzie D.A., Pearson B.M., Lapidus A., Dalin E., Tice H., Goltsman E., Land M., Hauser L. expand/collapse author list , Ivanova N., Kyrpides N.C., Walter J.
PLoS Genet. 7:E1001314-E1001314(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 20016.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000705 Genomic DNA. Translation: ABQ82719.1.
RefSeqYP_001271056.1. NC_009513.1.

3D structure databases

ProteinModelPortalA5VIP5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING557436.Lreu_0451.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABQ82719; ABQ82719; Lreu_0451.
GeneID5188855.
KEGGlre:Lreu_0451.
PATRIC22254021. VBILacReu87937_0467.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1435.
HOGENOMHOG000076391.
KOK00857.
OMARTICHCG.
OrthoDBEOG69D3J2.
ProtClustDBCLSK2326145.

Enzyme and pathway databases

BioCycLREU557436:GC7Y-469-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5VIP5_LACRD
AccessionPrimary (citable) accession number: A5VIP5
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: April 16, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)