A5VI87 (A5VI87_LACRD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 2 HAMAP MF_01039
Short name=BPG-dependent PGAM 2 HAMAP MF_01039
Short name=PGAM 2 HAMAP MF_01039
Short name=Phosphoglyceromutase 2 HAMAP MF_01039
Short name=dPGM 2 HAMAP MF_01039
EC=5.4.2.1 HAMAP MF_01039

Gene names

Name:	gpmA2 HAMAP MF_01039
Ordered Locus Names:	Lreu_0291

Organism

Lactobacillus reuteri (strain DSM 20016) [Complete proteome] [HAMAP] EMBL ABQ82561.1

Taxonomic identifier

557436 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	236 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01039
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01039
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01039
Sequence similarities	Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. HAMAP MF_01039

Ontologies

Keywords
Biological process	Glycolysis HAMAP MF_01039
Molecular function	Isomerase HAMAP MF_01039 EMBL ABQ82561.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: HAMAP
Molecular function	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	9	1	Tele-phosphohistidine intermediate By similarity HAMAP MF_01039
	Active site	176	1	By similarity HAMAP MF_01039
	Site	60	1	Interaction with carboxyl group of phosphoglycerates By similarity HAMAP MF_01039

Sequences

	Sequence		Length	Mass (Da)
	A5VI87 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: 2D5B42C8DAB2E84C	FASTA	236	27,388
	10 20 30 40 50 60 MAELVIVRHG QSQANRDNIF TGWTDVPLTP KGIEQGELVG KELLRLGIQF SDAYTSYMER 70 80 90 100 110 120 AIMTTNIILE EINQLYIPVH KTWRLNERHY GALSGRNKDE VKKEIGAEQL HKWRRGFKDL 130 140 150 160 170 180 PPQLKERQHD RRYDRLGVKI PLSESLEMTL QRLLPYWQDH IAPRLIDGHN QLIVAHGSSL 190 200 210 220 230 RALIKYLDGI SDDDIDKVEV PNGKPILYRF DDHLNVIKKT FITMDGEIDD NTRISK

References

[1]

"The evolution of host specialization in the vertebrate gut symbiont Lactobacillus reuteri." Frese S.A., Benson A.K., Tannock G.W., Loach D.M., Kim J., Zhang M., Oh P.L., Heng N.C., Patil P.B., Juge N., Mackenzie D.A., Pearson B.M., Lapidus A., Dalin E., Tice H., Goltsman E., Land M., Hauser L. , Ivanova N., Kyrpides N.C., Walter J. PLoS Genet. 7:E1001314-E1001314(2011) [PubMed: 21379339] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 20016.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000705 Genomic DNA. Translation: ABQ82561.1.
RefSeq	YP_001270898.1. NC_009513.1.
3D structure databases
ProteinModelPortal	A5VI87.
ModBase	Search...
Protein-protein interaction databases
STRING	A5VI87.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5188746.
GenomeReviews	Gene locus Lreu_0291 in contig CP000705_GR.
KEGG	lre:Lreu_0291.
PATRIC	22253680. VBILacReu87937_0299.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG658938.
OMA	ESTANRD.
ProtClustDB	CLSK2326081.
Family and domain databases
HAMAP	MF_01039. PGAM_GpmA. [Tree]
InterPro	IPR013078. His_Pase_superF_clade-1. IPR001345. PG/BPGM_mutase_AS. IPR005952. Phosphogly_mut1. [Graphical view]
KO	K01834.
PANTHER	PTHR11931. Phosphogly_mut1. 1 hit.
Pfam	PF00300. His_Phos_1. 1 hit. [Graphical view]
SMART	SM00855. PGAM. 1 hit. [Graphical view]
TIGRFAMs	TIGR01258. Pgm_1. 1 hit.
PROSITE	PS00175. PG_MUTASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5VI87_LACRD

Accession

Primary (citable) accession number: A5VI87

Entry history

Integrated into UniProtKB/TrEMBL:	July 10, 2007
Last sequence update:	July 10, 2007
Last modified:	December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)