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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Lactobacillus reuteri (strain DSM 20016)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:Lreu_0261
OrganismiLactobacillus reuteri (strain DSM 20016)
Taxonomic identifieri557436 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000001991 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000575521 – 186Peptidyl-tRNA hydrolaseAdd BLAST186

Proteomic databases

PRIDEiA5VI57

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA5VI57
SMRiA5VI57
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000004797
KOiK01056
OMAiRYAHTRH

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01195 PEPT_TRNA_HYDROL_1, 1 hit

Sequencei

Sequence statusi: Complete.

A5VI57-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKMIVGLGNI GTRYDETRHN TGFMVVDQLA RDYHLGAFTH LKQEAVAVSG
60 70 80 90 100
VINGEKVMLV KPTTFMNDSG RAVGPLVDYY DIDLDDLVIV NDDLDMPVGK
110 120 130 140 150
VRLKTHGASG GHNGLKSIIS VLGTKNFNRV KVGIDHPQHG TVVSHVLGKF
160 170 180
SKEERPKFDQ AVEQAEHALE DWINGEDFAK LMNAYN
Length:186
Mass (Da):20,530
Last modified:July 10, 2007 - v1
Checksum:i2BCEB842FA7BE882
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000705 Genomic DNA Translation: ABQ82531.1
RefSeqiWP_011953390.1, NZ_AZDD01000024.1

Genome annotation databases

EnsemblBacteriaiABQ82531; ABQ82531; Lreu_0261
GeneIDi5189338
KEGGilre:Lreu_0261
PATRICifig|557436.17.peg.905

Similar proteinsi

Entry informationi

Entry nameiPTH_LACRD
AccessioniPrimary (citable) accession number: A5VI57
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 10, 2007
Last modified: May 23, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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