A5VHY4 (A5VHY4_LACRD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrB HAMAP MF_01400
EC=1.8.4.12 HAMAP MF_01400

Alternative name(s):
Peptide-methionine (R)-S-oxide reductase HAMAP MF_01400

Gene names

Name:	msrB HAMAP MF_01400
Ordered Locus Names:	Lreu_0188

Organism

Lactobacillus reuteri (strain DSM 20016) [Complete proteome] [HAMAP] EMBL ABQ82458.1

Taxonomic identifier

557436 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	142 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Sequence similarities	Belongs to the MsrB Met sulfoxide reductase family. HAMAP MF_01400

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01400 SAAS SAAS002579 EMBL ABQ82458.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	114	1	Nucleophile By similarity HAMAP MF_01400

Sequences

	Sequence		Length	Mass (Da)
	A5VHY4 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: 58F4B096DF339CBF	FASTA	142	16,101
	10 20 30 40 50 60 MDKNELKKLT PMQYAVTQMG VTEKPYSGKY DRFDEPGIYV DVVSGEPLFS SLDKYDAGCG 70 80 90 100 110 120 WPAFTKPIKK RVLTEKRDQS FGMERTEVRS KEADSHLGHV FTDGPTDRGG LRYCINSAAL 130 140 QFIPVDKLQE KGYGEYLSLF DK

References

[1]

"The evolution of host specialization in the vertebrate gut symbiont Lactobacillus reuteri." Frese S.A., Benson A.K., Tannock G.W., Loach D.M., Kim J., Zhang M., Oh P.L., Heng N.C., Patil P.B., Juge N., Mackenzie D.A., Pearson B.M., Lapidus A., Dalin E., Tice H., Goltsman E., Land M., Hauser L. , Ivanova N., Kyrpides N.C., Walter J. PLoS Genet. 7:E1001314-E1001314(2011) [PubMed: 21379339] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 20016.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000705 Genomic DNA. Translation: ABQ82458.1.
RefSeq	YP_001270795.1. NC_009513.1.
3D structure databases
ProteinModelPortal	A5VHY4.
SMR	A5VHY4. Positions 5-134.
ModBase	Search...
Protein-protein interaction databases
STRING	A5VHY4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5188731.
GenomeReviews	Gene locus Lreu_0188 in contig CP000705_GR.
KEGG	lre:Lreu_0188.
PATRIC	22253454. VBILacReu87937_0196.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG715255.
OMA	FTDGPVD.
ProtClustDB	CLSK2326047.
Family and domain databases
HAMAP	MF_01400. MsrB. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. IPR011057. Mss4-like. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
KO	K07305.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
SUPFAM	SSF51316. Mss4_like. 1 hit.
TIGRFAMs	TIGR00357. TIGR00357. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5VHY4_LACRD

Accession

Primary (citable) accession number: A5VHY4

Entry history

Integrated into UniProtKB/TrEMBL:	July 10, 2007
Last sequence update:	July 10, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)