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Protein
Submitted name:

4-aminobutyrate aminotransferase

Gene

Swit_4211

Organism
Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. 4-aminobutyrate transaminase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. gamma-aminobutyric acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciSWIT392499:GHZK-4261-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
4-aminobutyrate aminotransferaseImported (EC:2.6.1.19Imported)
Gene namesi
Ordered Locus Names:Swit_4211Imported
OrganismiSphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)Imported
Taxonomic identifieri392499 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeSphingomonas
ProteomesiUP000001989: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3131 PotentialImportedAdd
BLAST
Chaini32 – 425394 PotentialImportedPRO_5000251163Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi392499.Swit_4211.

Structurei

3D structure databases

ProteinModelPortaliA5VE35.
SMRiA5VE35. Positions 3-424.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Keywords - Domaini

SignalImported

Phylogenomic databases

eggNOGiCOG0160.
HOGENOMiHOG000020206.
KOiK07250.
OMAiDFYAVKA.
OrthoDBiEOG6QVRHN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A5VE35-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTSNADLLAR RRQAVARGVA TAFPIFAARA DNAEIWDVDG QHYVDFAGGI
60 70 80 90 100
AVLNTGHRHP KVIAAVQEQL ALYTHMAFQV AAYEPYVALA ERLNALAPFT
110 120 130 140 150
GEAKTILFTT GAEATENAVK LARAATGRSA VIAFGGGFHG RTLLAMAMTG
160 170 180 190 200
KVAPYKQQFG PMPGEIFHVP FPVAAHGGSV EETLRAIEMV FRVAVEPGRV
210 220 230 240 250
AALIIEPILG EGGFYEAPVE LLRALRALCD RHGIILIADE VQTGFGRTGR
260 270 280 290 300
MFAIEHSGVE PDLVTVAKSL AGGFPLSGVI GRSAIMEASE PGGMGGTYGG
310 320 330 340 350
NPVACAAALA VLDVIAEEQL LDRAVAIGAR IKERLRLLAR RNDLVPITEI
360 370 380 390 400
RGPGAMIGFD IVTSRTGYEP DPETTRRVVE AAREAGLILL SCGIHGNVIR
410 420
ILVPLTVPDD ILDAGLAKLE QALAA
Length:425
Mass (Da):44,891
Last modified:July 10, 2007 - v1
Checksum:iF598CD0D73940FED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000699 Genomic DNA. Translation: ABQ70551.1.
RefSeqiWP_012050389.1. NC_009511.1.
YP_001264689.1. NC_009511.1.

Genome annotation databases

EnsemblBacteriaiABQ70551; ABQ70551; Swit_4211.
GeneIDi5199630.
KEGGiswi:Swit_4211.
PATRICi23687723. VBISphWit55028_4789.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000699 Genomic DNA. Translation: ABQ70551.1.
RefSeqiWP_012050389.1. NC_009511.1.
YP_001264689.1. NC_009511.1.

3D structure databases

ProteinModelPortaliA5VE35.
SMRiA5VE35. Positions 3-424.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi392499.Swit_4211.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ70551; ABQ70551; Swit_4211.
GeneIDi5199630.
KEGGiswi:Swit_4211.
PATRICi23687723. VBISphWit55028_4789.

Phylogenomic databases

eggNOGiCOG0160.
HOGENOMiHOG000020206.
KOiK07250.
OMAiDFYAVKA.
OrthoDBiEOG6QVRHN.

Enzyme and pathway databases

BioCyciSWIT392499:GHZK-4261-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RW1 / DSM 6014 / JCM 10273Imported.

Entry informationi

Entry nameiA5VE35_SPHWW
AccessioniPrimary (citable) accession number: A5VE35
Entry historyi
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: February 4, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.