A5VDB4 (A5VDB4_SPHWW) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Arginine--tRNA ligase HAMAP MF_00123
EC=6.1.1.19 HAMAP MF_00123

Alternative name(s):
Arginyl-tRNA synthetase HAMAP MF_00123

Gene names

Name:	argS HAMAP MF_00123
Ordered Locus Names:	Swit_3935

Organism

Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273) [Complete proteome] [HAMAP]

Taxonomic identifier

392499 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Sphingomonas

Protein attributes

Sequence length	576 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity. HAMAP MF_00123
Subcellular location	Cytoplasm By similarity HAMAP MF_00123.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP MF_00123 RuleBase RU003489

Ontologies

Keywords
Biological process	Protein biosynthesis HAMAP MF_00123 RuleBase RU003489
Cellular component	Cytoplasm HAMAP MF_00123
Ligand	ATP-binding HAMAP MF_00123 RuleBase RU003489 Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase HAMAP MF_00123 RuleBase RU003489 EMBL ABQ70280.1 Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Motif	132 – 142	11	"HIGH" region By similarity HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	A5VDB4 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: 29A0EC420DD35010	FASTA	576	62,086
	10 20 30 40 50 60 MTTLYASFAD RIGAILDDLQ ASGALPAGLD RRNVAVEPPR DPAHGDLATN AAMVLAKPAG 70 80 90 100 110 120 TNPRALAELI VPKLAALPEI ASAEVAGPGF INVRLTEQSW RDELAGILSS GGDYGRTATG 130 140 150 160 170 180 RGTRVNVEYV SANPTGPMHM GHCRGAVVGD ALAALLEFAG YAVTREYYVN DAGAQVQTLA 190 200 210 220 230 240 RSAHLRYREA LGETIEIPEG FYPGDYLIPI GQALAAEFGD AYVGKPESAW LDLFREKTVA 250 260 270 280 290 300 AMMDMIRADL ALLGIEHEVF ASEAAVQKAG KVDVALDRLR GEGLVYEGTL EPPKGELPDD 310 320 330 340 350 360 WEPTEMTLFK ATAFGDDSDR PVRKSDGGLT YFGTDLAYHA QKAETADMLI DIWGADHAGT 370 380 390 400 410 420 VKRIKAAVQA LTGGKVAFDV KLVQMVRLLR GGEPVKMSKR SGSFVTLADV VREVGKDVVR 430 440 450 460 470 480 FTMLTRKADA QMDFDFAKVV EASKDNPVFY VQYAHARGRS LHRRAAEAGI DLAPAADLSL 490 500 510 520 530 540 LDAEELALVK LAAQFPRIVE GAAQAHEPHR IAFYLYDLAA MFHALWNRGN DDPARRFLLS 550 560 570 DKPEITRARL ALSDAIGQII RNGLGVMGVT AAEEMQ

References

[1]

"Complete sequence of chromosome of Sphingomonas wittichii RW1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Halden R.U., Miller T.R., Salzberg S.L., Eisen J.A., Richardson P. Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RW1 / DSM 6014 / JCM 10273.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000699 Genomic DNA. Translation: ABQ70280.1.
RefSeq	YP_001264418.1. NC_009511.1.
3D structure databases
ProteinModelPortal	A5VDB4.
ModBase	Search...
Protein-protein interaction databases
STRING	A5VDB4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5199806.
GenomeReviews	Gene locus Swit_3935 in contig CP000699_GR.
KEGG	swi:Swit_3935.
NMPDR	fig|392499.4.peg.4014.
PATRIC	23687145. VBISphWit55028_4503.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0018.
HOGENOM	HBG695395.
OMA	ETIRGCL.
ProtClustDB	PRK01611.
Family and domain databases
HAMAP	MF_00123. Arg_tRNA_synth. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ia. IPR015945. Arg-tRNA-synth_Ia_core. IPR005148. Arg-tRNA-synth_N. IPR008909. DALR_anticod-bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_1a_anticodon-bd. [Graphical view]
Gene3D	G3DSA:3.30.1360.70. Arg-tRNA-synth_Ic_N. 1 hit. G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KO	K01887.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
SMART	SM01016. Arg_tRNA_synt_N. 1 hit. SM00836. DALR_1. 1 hit. [Graphical view]
SUPFAM	SSF55190. Arg-tRNA-synth_Ic_N. 1 hit. SSF47323. tRNAsyn_1a_bind. 1 hit.
TIGRFAMs	TIGR00456. ArgS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5VDB4_SPHWW

Accession

Primary (citable) accession number: A5VDB4

Entry history

Integrated into UniProtKB/TrEMBL:	July 10, 2007
Last sequence update:	July 10, 2007
Last modified:	January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)