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A5VBA0

- TRPC_SPHWW

UniProt

A5VBA0 - TRPC_SPHWW

Protein

Indole-3-glycerol phosphate synthase

Gene

trpC

Organism
Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (10 Jul 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. indole-3-glycerol-phosphate synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tryptophan biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Decarboxylase, Lyase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

    Enzyme and pathway databases

    BioCyciSWIT392499:GHZK-3254-MONOMER.
    UniPathwayiUPA00035; UER00043.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Indole-3-glycerol phosphate synthaseUniRule annotation (EC:4.1.1.48UniRule annotation)
    Short name:
    IGPSUniRule annotation
    Gene namesi
    Name:trpCUniRule annotation
    Ordered Locus Names:Swit_3219
    OrganismiSphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)
    Taxonomic identifieri392499 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeSphingomonas
    ProteomesiUP000001989: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 264264Indole-3-glycerol phosphate synthasePRO_1000018553Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi392499.Swit_3219.

    Structurei

    3D structure databases

    ProteinModelPortaliA5VBA0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrpC family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0134.
    HOGENOMiHOG000230463.
    KOiK01609.
    OMAiRKDFMFE.
    OrthoDBiEOG6WT8JX.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00134_B. IGPS_B.
    InterProiIPR013785. Aldolase_TIM.
    IPR013798. Indole-3-glycerol_P_synth.
    IPR001468. Indole-3-GlycerolPSynthase_CS.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00218. IGPS. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.
    PROSITEiPS00614. IGPS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A5VBA0-1 [UniParc]FASTAAdd to Basket

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    MSNKLTEICD TKRDHVARRK AETSFAELTA RAKAADAPRG FRAALDRKVA    50
    EGGYGLIAEI KKASPSKGLI RPDFDPPAHA RAYQAAGAAC LSVLTDMPYF 100
    QGHDDYLVQA RAACALPALR KDFIVDPWQV TEARALGADA ILIIVAALDD 150
    GQMAEIEAAA IEHGMDALVE VHDADEFDRA LRLRSRLIGV NNRDLRDFTI 200
    DFARTYELVG HAPAGCTFVA ESGLGSKADL DAMADHGVGC FLVGESLMRQ 250
    DDLAAATRRL LTGA 264
    Length:264
    Mass (Da):28,408
    Last modified:July 10, 2007 - v1
    Checksum:iDC245DBEA71E69B7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000699 Genomic DNA. Translation: ABQ69566.1.
    RefSeqiYP_001263704.1. NC_009511.1.

    Genome annotation databases

    EnsemblBacteriaiABQ69566; ABQ69566; Swit_3219.
    GeneIDi5196199.
    KEGGiswi:Swit_3219.
    PATRICi23685655. VBISphWit55028_3770.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000699 Genomic DNA. Translation: ABQ69566.1 .
    RefSeqi YP_001263704.1. NC_009511.1.

    3D structure databases

    ProteinModelPortali A5VBA0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 392499.Swit_3219.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABQ69566 ; ABQ69566 ; Swit_3219 .
    GeneIDi 5196199.
    KEGGi swi:Swit_3219.
    PATRICi 23685655. VBISphWit55028_3770.

    Phylogenomic databases

    eggNOGi COG0134.
    HOGENOMi HOG000230463.
    KOi K01609.
    OMAi RKDFMFE.
    OrthoDBi EOG6WT8JX.

    Enzyme and pathway databases

    UniPathwayi UPA00035 ; UER00043 .
    BioCyci SWIT392499:GHZK-3254-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00134_B. IGPS_B.
    InterProi IPR013785. Aldolase_TIM.
    IPR013798. Indole-3-glycerol_P_synth.
    IPR001468. Indole-3-GlycerolPSynthase_CS.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00218. IGPS. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    PROSITEi PS00614. IGPS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RW1 / DSM 6014 / JCM 10273.

    Entry informationi

    Entry nameiTRPC_SPHWW
    AccessioniPrimary (citable) accession number: A5VBA0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: July 10, 2007
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3