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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei168 – 1681UniRule annotation
Active sitei596 – 5961UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciSWIT392499:GHZK-3170-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Swit_3135Imported
OrganismiSphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)Imported
Taxonomic identifieri392499 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeSphingomonas
ProteomesiUP000001989 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi392499.Swit_3135.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5VB17-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPAFAGMTVE RLSGQTPAAA TSFSVDRAFI ASQHRAMSST PPITQNPDIR
60 70 80 90 100
FLGRLLGDVI RVYGGEALFR RIEYIRSASV DRARGIVGSH EIDSGLGALT
110 120 130 140 150
LDDTLAFVRG FMLFSMLANL AEDRQGIAAE PGADVAAALD RLEKEGISRA
160 170 180 190 200
KVVEMLDRAL IVPVLTAHPT EVRRKSMIDH RNKIAELMTL KDIGRTETVD
210 220 230 240 250
GDLIDQAIYR QIALLWQTRP LRRERLYVAD EVETALAYLR DIFLPTLPAL
260 270 280 290 300
YSRWQRALGH RPASFLKPGS WIGGDRDGNP FVTADSLRLA LSRSAETVIG
310 320 330 340 350
YYLRELHELG AELSISTELA EVTWEVEKLA EASGDKSSTR SDEPYRRAIT
360 370 380 390 400
GIYSRLSKTY EKLTGRLPAR LPATDAEGGA YEDPAALRAD LVEIAHALNR
410 420 430 440 450
TGADSLAGNG ALGRLIRAVE TFGFHLATLD MRQNADVHER VVADLLRVAG
460 470 480 490 500
VEADYGALDE PARVALLRSE LASKRLLRTP FGAYADETLS ELAIVEAAAE
510 520 530 540 550
AHRRYGPAAI TTYLISKAES VSDMLEVNIL LKEAGLFVPG DPPTAAIMAV
560 570 580 590 600
PLFETIGDLD RAPEVMTQWF ALPEVAAITA ARGHQEVMVG YSDSNKDGGY
610 620 630 640 650
LTSVWSLHEA SSALKPVFAK ANSAIQLFHG RGGAVGRGGG SSFAAILAQP
660 670 680 690 700
HGTVQGRIRI TEQGEVIAAK YGTRESAAAN LEAMASATLL ATLEEDALQP
710 720 730 740 750
KDAKRFFAAM DEISANAFKA YRGLVYDTEG FRTFFRQMTP IAEIADLKIG
760 770 780 790 800
SRPASRTKSD RIEDLRAIPW VFSWAQARVM LPGWYGVGHG LKGFKDIGLL
810 820 830 840 850
REMLEAWPFF QSTLANLEMV LAKSDMDIAE RYVALVEDEA MGRDIFGRIR
860 870 880 890 900
DGWQRTQEAL LSVTRQTRLL QKNPSLDQSI RLRLPYIEPL NLLQIELLKR
910 920
HRAGEDDPRV REGIQLSINA IATALRNSG
Length:929
Mass (Da):101,903
Last modified:July 9, 2007 - v1
Checksum:iB09DB7547F3F8E52
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000699 Genomic DNA. Translation: ABQ69483.1.
RefSeqiWP_012049328.1. NC_009511.1.
YP_001263621.1. NC_009511.1.

Genome annotation databases

EnsemblBacteriaiABQ69483; ABQ69483; Swit_3135.
KEGGiswi:Swit_3135.
PATRICi23685481. VBISphWit55028_3683.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000699 Genomic DNA. Translation: ABQ69483.1.
RefSeqiWP_012049328.1. NC_009511.1.
YP_001263621.1. NC_009511.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi392499.Swit_3135.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ69483; ABQ69483; Swit_3135.
KEGGiswi:Swit_3135.
PATRICi23685481. VBISphWit55028_3683.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciSWIT392499:GHZK-3170-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RW1 / DSM 6014 / JCM 10273Imported.

Entry informationi

Entry nameiA5VB17_SPHWW
AccessioniPrimary (citable) accession number: A5VB17
Entry historyi
Integrated into UniProtKB/TrEMBL: July 9, 2007
Last sequence update: July 9, 2007
Last modified: March 31, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.