A5VA39 (A5VA39_SPHWW) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA gyrase subunit B RuleBase RU003363
EC=5.99.1.3 RuleBase RU003363

Gene names

Ordered Locus Names:

Swit_2802

Organism

Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273) [Complete proteome] [HAMAP]

Taxonomic identifier

392499 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Sphingomonas

Protein attributes

Sequence length	826 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings By similarity. RuleBase RU003363
Catalytic activity	ATP-dependent breakage, passage and rejoining of double-stranded DNA. RuleBase RU003363 SAAS SAAS002288
Sequence similarities	Belongs to the type II topoisomerase family. RuleBase RU000380 Contains 1 Toprim domain. SAAS SAAS002288

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS002288 RuleBase RU000380 Nucleotide-binding
Molecular function	Isomerase Topoisomerase SAAS SAAS002288 RuleBase RU000380
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA topological change Inferred from electronic annotation. Source: InterPro
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA topoisomerase (ATP-hydrolyzing) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5VA39 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: 5F9516B2837D819E	FASTA	826	90,772
	10 20 30 40 50 60 MTNETENSPN ANSYGADSIK VLKGLDAVRK RPGMYIGDTD DGSGLHHMVF EVSDNAIDEA 70 80 90 100 110 120 LAGHCDRIVI TLNPDGSVSV EDNGRGIPTG IHAEEGVSAA EVIMTQLHAG GKFDNTNDAN 130 140 150 160 170 180 AYKVSGGLHG VGVSVVNALS DVLDLTIWRD GEEHYMRFQR GDAVAPLKVV GPANGKKGTK 190 200 210 220 230 240 VTFLPSPETF KITEFDFDKL EHRYRELAFL NSGVRLFLAD ERHAERKEIE LFYEGGIAAF 250 260 270 280 290 300 VKYLDRTKVA LMPDPVAIMG QRDDVGIDVA LEWNDSYYEQ VLCFTNNIPQ RDGGTHLAAF 310 320 330 340 350 360 RAALTRTLNN YAEKSGALKK EKVSLTGDDM REGLTAIVSV KLPDPKFSSQ TKDKLVSSEV 370 380 390 400 410 420 RQPLESLMAD KLAEWLEENP AHARSIIQKV IDAAAAREAA RKARELTRRK GVMDIASLPG 430 440 450 460 470 480 KLADCQERDP SKCELFLVEG DSAGGSAKQG RDRVYQAILP LKGKILNVER ARFDRMLSSK 490 500 510 520 530 540 EVGTLIQAMG TGIGRDDFNL EKLRYHKIVI MTDADVDGAH IRTLLLTFFY RHMKPIIENG 550 560 570 580 590 600 HLYIAQPPLY KVAKGRSEVY LKDDAALDEY LVTGGLGAMM LETPSGARSG DDLRVLVEHA 610 620 630 640 650 660 RRMRSLMRFV PKRYDPVIVE ALALTGALDP ESGDEGHRAS ARAVAAWMGR IDPEAAWSGD 670 680 690 700 710 720 LAEDGGYHLQ RLWRGVTDHH LIDPAFLRSA EARKLHALAA EQAESYARSA RLVPLRSAAA 730 740 750 760 770 780 PTGDDEDEPI VDTRGTAVHQ PSNLLDAVLA AGRKGMSIQR YKGLGEMNAE QLWETTLDPA 790 800 810 820 NRAMLKVEVA QADVADEIFT RLMGDVVEPR REFIQENALS VANLDV

References

[1]

"Complete sequence of chromosome of Sphingomonas wittichii RW1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Halden R.U., Miller T.R., Salzberg S.L., Eisen J.A., Richardson P. Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RW1 / DSM 6014 / JCM 10273.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000699 Genomic DNA. Translation: ABQ69155.1.
RefSeq	YP_001263293.1. NC_009511.1.
3D structure databases
ProteinModelPortal	A5VA39.
SMR	A5VA39. Positions 19-392.
ModBase	Search...
Protein-protein interaction databases
STRING	A5VA39.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5196622.
GenomeReviews	Gene locus Swit_2802 in contig CP000699_GR.
KEGG	swi:Swit_2802.
NMPDR	fig|392499.4.peg.2964.
PATRIC	23684775. VBISphWit55028_3331.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0187.
HOGENOM	HBG304889.
OMA	DCSSRDP.
ProtClustDB	PRK14939.
Family and domain databases
HAMAP	MF_01898. GyrB. [Tree]
InterPro	IPR003594. ATPase-like_ATP-bd. IPR011557. GyrB. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR001241. Topo_IIA. IPR013759. Topo_IIA_B/N_ab. IPR002288. Topo_IIA_B_C. IPR013506. Topo_IIA_bsu_dom2. IPR013760. Topo_IIA_cen. IPR018522. TopoIIA_CS. IPR006171. Toprim_domain. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit. G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 2 hits.
KO	K02470.
Pfam	PF00204. DNA_gyraseB. 1 hit. PF00986. DNA_gyraseB_C. 1 hit. PF02518. HATPase_c. 1 hit. PF01751. Toprim. 1 hit. [Graphical view]
PRINTS	PR00418. TPI2FAMILY.
SMART	SM00387. HATPase_c. 1 hit. SM00433. TOP2c. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMs	TIGR01059. GyrB. 1 hit.
PROSITE	PS00177. TOPOISOMERASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5VA39_SPHWW

Accession

Primary (citable) accession number: A5VA39

Entry history

Integrated into UniProtKB/TrEMBL:	July 10, 2007
Last sequence update:	July 10, 2007
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)