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A5VA34 (GLSA_SPHWW) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:Swit_2796
OrganismSphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273) [Complete proteome] [HAMAP]
Taxonomic identifier392499 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeSphingomonas

Protein attributes

Sequence length318 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 318318Glutaminase HAMAP-Rule MF_00313
PRO_0000336041

Sites

Binding site691Substrate By similarity
Binding site1191Substrate By similarity
Binding site1651Substrate By similarity
Binding site1721Substrate By similarity
Binding site1961Substrate By similarity
Binding site2481Substrate By similarity
Binding site2661Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
A5VA34 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 1AD368F661EC78C6

FASTA31833,703
        10         20         30         40         50         60 
MPVTVAPDLQ AIVDRIAAEM AGREERGKVA DYIPGLARVD PKHFGIAVAT HDGRMFAAGD 

        70         80         90        100        110        120 
ADMAFSIQSV SKVFALTIAL GKVGDALWKR VGREPSGNAF NSIVQLEAEQ GIPRNPFINA 

       130        140        150        160        170        180 
GAIVVSDVVL AGHAPKEAIG EILRFVRDLA GDDGIVVDDE VAQGEADTGF RNAALANYMR 

       190        200        210        220        230        240 
SFGNILHPVD QVLGVYFHQC ALAMSCRQLA RAGRFLMHEG QHPDTGFNIV SPMRARRINA 

       250        260        270        280        290        300 
LMMLCGHYDG SGEFAFRVGI PGKSGVGGGI LCVVPGIASI AVWSPGLNER GNSTLGSLAL 

       310 
ERLAAATGWS VFNQREPG 

« Hide

References

[1]"Complete sequence of chromosome of Sphingomonas wittichii RW1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Halden R.U., Miller T.R., Salzberg S.L., Eisen J.A., Richardson P.
Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RW1 / DSM 6014 / JCM 10273.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000699 Genomic DNA. Translation: ABQ69150.1.
RefSeqYP_001263288.1. NC_009511.1.

3D structure databases

ProteinModelPortalA5VA34.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING392499.Swit_2796.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABQ69150; ABQ69150; Swit_2796.
GeneID5196866.
KEGGswi:Swit_2796.
PATRIC23684763. VBISphWit55028_3325.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMARINALML.
OrthoDBEOG6N94BK.
ProtClustDBPRK00971.

Enzyme and pathway databases

BioCycSWIT392499:GHZK-2830-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_SPHWW
AccessionPrimary (citable) accession number: A5VA34
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 10, 2007
Last modified: February 19, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families