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A5V9W3

- G6PI_SPHWW

UniProt

A5V9W3 - G6PI_SPHWW

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Protein
Glucose-6-phosphate isomerase
Gene
pgi, Swit_2723
Organism
Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei332 – 3321Proton donor By similarity
Active sitei363 – 3631 By similarity
Active sitei473 – 4731 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciSWIT392499:GHZK-2757-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:Swit_2723
OrganismiSphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)
Taxonomic identifieri392499 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeSphingomonas
ProteomesiUP000001989: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 500500Glucose-6-phosphate isomeraseUniRule annotation
PRO_1000014024Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi392499.Swit_2723.

Structurei

3D structure databases

ProteinModelPortaliA5V9W3.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiCGNELDN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5V9W3-1 [UniParc]FASTAAdd to Basket

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MTEAKAAWNA LRDTPATSLT ELFTNEPDRL SRLSMEEAGI LFDFSKTHLS    50
AALIDRFAAL AEASGFAARR DALFAGAAVN VTEDRAAEHP AERGQGAPDS 100
VARARGFHAR MRGMIDAIEA EVFGPIRHIL HVGIGGSALG PDLLVDALGR 150
DAGRYEVAVV SNVDGAALDA VFRRFDPQAT LLVVASKTFT TTETMLNARS 200
VLAWMEEDNV EDPYSRVIAL TAAPEKAVEW GIDETRILPF SESVGGRYSL 250
WSSIGFPVAL ALGWDAFEEL LEGAAAMDRH FRLAPPSANI PLLAAFVDQY 300
YSVLRGAETR AVFAYDERLR LLPSYLQQLE MESNGKGVKA DGSPVDGPTA 350
AITWGGVGTD AQHAVFQLLH QGTRLVPVEF VAAIEPDHVL DDAHHRTLLV 400
NCFAQGAALM AGRDNGDPAR AYPGDRPSTT ILLDRLDPGR LGALIAFYEH 450
RTFANAVLLG INPFDQFGVE LGKEIARSIE SEGTDRFDPS TRALIARALG 500
Length:500
Mass (Da):53,935
Last modified:July 10, 2007 - v1
Checksum:iCE780A5B7DC96FF2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000699 Genomic DNA. Translation: ABQ69079.1.
RefSeqiYP_001263217.1. NC_009511.1.

Genome annotation databases

EnsemblBacteriaiABQ69079; ABQ69079; Swit_2723.
GeneIDi5196880.
KEGGiswi:Swit_2723.
PATRICi23684613. VBISphWit55028_3250.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000699 Genomic DNA. Translation: ABQ69079.1 .
RefSeqi YP_001263217.1. NC_009511.1.

3D structure databases

ProteinModelPortali A5V9W3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 392499.Swit_2723.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABQ69079 ; ABQ69079 ; Swit_2723 .
GeneIDi 5196880.
KEGGi swi:Swit_2723.
PATRICi 23684613. VBISphWit55028_3250.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OMAi CGNELDN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci SWIT392499:GHZK-2757-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RW1 / DSM 6014 / JCM 10273.

Entry informationi

Entry nameiG6PI_SPHWW
AccessioniPrimary (citable) accession number: A5V9W3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 10, 2007
Last modified: June 11, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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