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A5V8U3 (A5V8U3_SPHWW) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Triosephosphate isomerase HAMAP MF_00147
Short name=TIM HAMAP MF_00147
EC=5.3.1.1 HAMAP MF_00147
Alternative name(s):
Triose-phosphate isomerase HAMAP MF_00147
Gene names
Name:tpiA HAMAP MF_00147
Ordered Locus Names:Swit_2350
OrganismSphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273) [Complete proteome] [HAMAP]
Taxonomic identifier392499 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Sphingomonas

Protein attributes

Sequence length250 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glyceraldehyde 3-phosphate = glycerone phosphate. HAMAP MF_00147 RuleBase RU000517

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_00147 RuleBase RU003527

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1. HAMAP MF_00147 RuleBase RU003527

Subunit structure

Homodimer By similarity. HAMAP MF_00147

Subcellular location

Cytoplasm By similarity HAMAP MF_00147.

Sequence similarities

Belongs to the triosephosphate isomerase family. RuleBase RU004162 HAMAP MF_00147

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site931Electrophile By similarity HAMAP MF_00147
Active site1631Proton acceptor By similarity HAMAP MF_00147
Binding site101Substrate By similarity HAMAP MF_00147
Binding site121Substrate By similarity HAMAP MF_00147

Sequences

Sequence LengthMass (Da)Tools
A5V8U3 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: B04B569656F35832

FASTA25024,735
        10         20         30         40         50         60 
MGLRKLVAGN WKMNGSLGSL AELDAIAAAA KAQASVDVAV CPPFTLIAPA AARQPGLAIG 

        70         80         90        100        110        120 
AQDCHAQPKG AHTGCVSAAM LVEAGARLAI VGHSERRADQ HETDAEVRAK AAAAIAAGLT 

       130        140        150        160        170        180 
AIVCVGETEA ERDAGRAVAV VEGQLDGSIP RDGTAATLVV AYEPVWAIGT GRTPSTADVA 

       190        200        210        220        230        240 
EMHAAIRARL GALLGGEGAG VRILYGGSVK PDNAAELLAV ADVDGALVGG ASLTAAQFVP 

       250 
IIEGAAAASV

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References

[1]"Complete sequence of chromosome of Sphingomonas wittichii RW1."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Halden R.U., Miller T.R., Salzberg S.L., Eisen J.A., Richardson P.
Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RW1 / DSM 6014 / JCM 10273.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000699 Genomic DNA. Translation: ABQ68709.1.
RefSeqYP_001262847.1. NC_009511.1.

3D structure databases

ProteinModelPortalA5V8U3.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5V8U3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5199678.
GenomeReviewsGene locus Swit_2350 in contig CP000699_GR.
KEGGswi:Swit_2350.
NMPDRfig|392499.4.peg.2561.
PATRIC23683833. VBISphWit55028_2871.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0149.
HOGENOMHBG708281.
OMAANTVIAY.
ProtClustDBPRK00042.

Family and domain databases

HAMAPMF_00147_B. TIM_B.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR022896. TrioseP_Isoase_bac/euk.
IPR000652. Triosephosphate_isomerase.
IPR020861. Triosephosphate_isomerase_AS.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01803.
PANTHERPTHR21139. Triophos_ismrse. 1 hit.
PfamPF00121. TIM. 1 hit.
[Graphical view]
SUPFAMSSF51351. Triophos_ismrse. 1 hit.
TIGRFAMsTIGR00419. Tim. 1 hit.
PROSITEPS00171. TIM_1. 1 hit.
PS51440. TIM_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5V8U3_SPHWW
AccessionPrimary (citable) accession number: A5V8U3
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info