A5V5B9 (A5V5B9_SPHWW) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2 HAMAP MF_01902
Ordered Locus Names:	Swit_1119

Organism

Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273) [Complete proteome] [HAMAP]

Taxonomic identifier

392499 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Sphingomonas

Protein attributes

Sequence length	1196 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004805
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS011708.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS011708 DNA replication HAMAP MF_01902 SAAS SAAS004805
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS011708
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004805 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5V5B9 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: E8E8547A4245AE1C	FASTA	1,196	133,042
	10 20 30 40 50 60 MSAEAVPFAE MVAATNYSFL RGASAAADMV AAARAAGHAG IGIADRNSVA GVVRAWDAVR 70 80 90 100 110 120 KAREEARKAG HADLAFKLAT GARLVFVDGT PDIVAYPATR RGWGRLTRLL TTGNRRAIKG 130 140 150 160 170 180 DCILFLDDLL GHLDDLLLIV IPGGEGLVLG EEGARPHPTW DGSMPSFPRK RESMDGGSLE 190 200 210 220 230 240 PERSVTVDSR FRENDGEKRE EIFPPSPQRR LGPMSLVTVD GVRVEDDPSP AASCERTDMD 250 260 270 280 290 300 PSLRWDDAVR RALSILKRAA PDRVWLGLSM PYSGRDRRRI ATYARLAKEV GVPLLATNDA 310 320 330 340 350 360 LYATPGQRPL HDVVTCIRLG LTLDEAGTRL AANGERHLKP GHEMARLFVD HPQAVAAGVA 370 380 390 400 410 420 LLDRIDFDLK QLKYEYPHEP VPEGWTPQGW LEHLVEKGIA WRYGPNPEQK VLDLVETELK 430 440 450 460 470 480 LVRDARYAYY FLTVHDVVAF ARGEKILCQG RGSAANSVIC YVLGITEVDP VHNKLLFSRF 490 500 510 520 530 540 ISEDRNEPPD IDVDFEHERR EEVMQHVYAR YGRHRAGIAA TVIHYRPRSA VREIAKVLGL 550 560 570 580 590 600 SEDVAAKLTS TIWGSYAATM EGKRFHETGF DPGNVEIARL NMLVEQLLTF PRHLSQHVGG 610 620 630 640 650 660 FVLTEDRLDE TVPIHNAAMD DRTFIEWDKD DIDALGLMKV DVLALGMLTC IRKAFALIQA 670 680 690 700 710 720 HTGTEYTLAT IPKERKEVYD MLCKGDSIGV FQVESRAQIN MLPRLRPRTL YDLVVQVAIV 730 740 750 760 770 780 RPGPIQGGMV HPYLKRRKEE REGRLVIDYP GPKGPDGAPE LEDVLSKTLG VPLFQEQAMK 790 800 810 820 830 840 LAIVAAKFTD GEANQLRRAM ATFRHVGTMP EFEGKMVEGM VARGYPRDFA ERCFAQIKGF 850 860 870 880 890 900 GSYGFPESHA QSFALLVYAS SYIKCRYPAV FACALLNSQP MGFYAPAQIV RDAREHGVEV 910 920 930 940 950 960 RAADVNRSGW DNSLEGPPGR LALRIGLRQV EGFRQAWADE IAKVRGQGAF ASIEELARRA 970 980 990 1000 1010 1020 KLPRRALRLL ADADAFRSLG LDRRAALWEA RRTPDGELPL FAAAKARELG EEPDAMLPAM 1030 1040 1050 1060 1070 1080 PLSEHVAADY QMTRLSLKGH PMQFLRDVFR REGVLSCAEV AQAKNGRRAK VAGVVLVRQR 1090 1100 1110 1120 1130 1140 PGEGKAIFIT LEDETGITNV LLWARTFEVQ RRQVMASRLM VVEGEIQKSP EGVVHLMGAI 1150 1160 1170 1180 1190 VDDRTAELDR LSEDHRATIE LLPADVFEHP QPPRDHVPRG SHPRNVRILP KSRDFH

References

[1]

"Complete sequence of chromosome of Sphingomonas wittichii RW1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Halden R.U., Miller T.R., Salzberg S.L., Eisen J.A., Richardson P. Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RW1 / DSM 6014 / JCM 10273.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000699 Genomic DNA. Translation: ABQ67485.1.
RefSeq	YP_001261623.1. NC_009511.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A5V5B9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5198731.
GenomeReviews	Gene locus Swit_1119 in contig CP000699_GR.
KEGG	swi:Swit_1119.
NMPDR	fig|392499.4.peg.1423.
PATRIC	23681302. VBISphWit55028_1612.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	LATNRNG.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR012340. NA-bd_OB-fold. IPR004365. NA-bd_OB_tRNA-helicase. IPR004805. PolC_alpha. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5V5B9_SPHWW

Accession

Primary (citable) accession number: A5V5B9

Entry history

Integrated into UniProtKB/TrEMBL:	July 10, 2007
Last sequence update:	July 10, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)