Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A5V4F8 (A5V4F8_SPHWW) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length378 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site401Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2601Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1391Substrate By similarity HAMAP-Rule MF_01201
Binding site3081Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue401N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
A5V4F8 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 45174E0DFCC5732C

FASTA37840,224
        10         20         30         40         50         60 
MTANDAAAGA ILRIDLDAII DNYRLIQQRA APAEVAAVVK ADAYGLGAAR VAAALRDAGC 

        70         80         90        100        110        120 
RRFFVAHLVE AARLREAIGD GVEIGVLNGL QPGAETACAE LGAVPVLNAL DQIERWAALA 

       130        140        150        160        170        180 
RASSARLPCM IQFDTGMSRL GLAPGEVRAL IDRPERLDGL DIRLIMSHLA CADEPERASN 

       190        200        210        220        230        240 
QHQAQAFDAF CARFPGIPRS LDNSGGALLP RAHHYDVVRA GIALYGGAPQ TGPNPMRPVV 

       250        260        270        280        290        300 
TLDARVIQLR TVEPGTAVGY GLTHRFDRPA RLATLSVGYA DGWPRSLGNR GAAYVAGHRA 

       310        320        330        340        350        360 
PIVGRISMDS LTIDVSDIPE ELLLPGSLIE LIGPHQSIDD VARDAGTISY EILTQLGHRY 

       370 
ARSYLPSPSL HQQKAAQA 

« Hide

References

[1]"Complete sequence of chromosome of Sphingomonas wittichii RW1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Halden R.U., Miller T.R., Salzberg S.L., Eisen J.A., Richardson P.
Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RW1 / DSM 6014 / JCM 10273.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000699 Genomic DNA. Translation: ABQ67174.1.
RefSeqYP_001261312.1. NC_009511.1.

3D structure databases

ProteinModelPortalA5V4F8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING392499.Swit_0807.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABQ67174; ABQ67174; Swit_0807.
GeneID5197425.
KEGGswi:Swit_0807.
PATRIC23680636. VBISphWit55028_1283.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031445.
KOK01775.
OMAFIMSHLA.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycSWIT392499:GHZK-820-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5V4F8_SPHWW
AccessionPrimary (citable) accession number: A5V4F8
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: July 9, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)