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A5V3T4 (A5V3T4_SPHWW) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
GTP cyclohydrolase 1 HAMAP MF_00223
EC=3.5.4.16 HAMAP MF_00223
Alternative name(s):
GTP cyclohydrolase I HAMAP MF_00223
Gene names
Name:folE HAMAP MF_00223
Ordered Locus Names:Swit_0582
OrganismSphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273) [Complete proteome] [HAMAP]
Taxonomic identifier392499 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Sphingomonas

Protein attributes

Sequence length206 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate. HAMAP MF_00223 SAAS SAAS001474

Pathway

Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1. HAMAP MF_00223 SAAS SAAS001474

Subunit structure

Homopolymer By similarity. HAMAP MF_00223

Sequence similarities

Belongs to the GTP cyclohydrolase I family. HAMAP MF_00223

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding961Zinc By similarity HAMAP MF_00223
Metal binding991Zinc By similarity HAMAP MF_00223
Metal binding1671Zinc By similarity HAMAP MF_00223

Sequences

Sequence LengthMass (Da)Tools
A5V3T4 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 3DA78DD7BDB6E246

FASTA20622,933
        10         20         30         40         50         60 
MSILGDDDEA LHGTPKGKIA VPEHVQEAIR TLIRWSGDNP DREGLLDTPS RVGRAWKEYC 

        70         80         90        100        110        120 
QGYDEDPSVH LSRTFEEVGG YDEIVLLRDI PFQSHCEHHM APIIGHAHIA YLPHSRVVGI 

       130        140        150        160        170        180 
SKLARVLHGF ARRLQIQERL TAEIADCIWT NLEPLGVAVV IHATHACMTA RGVRTPGVGM 

       190        200 
TTSRMMGVFR DDDRSRKEVL SLMGLG

« Hide

References

[1]"Complete sequence of chromosome of Sphingomonas wittichii RW1."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Halden R.U., Miller T.R., Salzberg S.L., Eisen J.A., Richardson P.
Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RW1 / DSM 6014 / JCM 10273.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000699 Genomic DNA. Translation: ABQ66950.1.
RefSeqYP_001261088.1. NC_009511.1.

3D structure databases

ProteinModelPortalA5V3T4.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5V3T4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5200413.
GenomeReviewsGene locus Swit_0582 in contig CP000699_GR.
KEGGswi:Swit_0582.
NMPDRfig|392499.4.peg.910.
PATRIC23680158. VBISphWit55028_1046.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0302.
HOGENOMHBG370191.
OMAEPREYLE.
ProtClustDBCLSK944465.

Family and domain databases

HAMAPMF_00223. FolE.
[Tree]
InterProIPR001474. GTP_CycHdrlase_I.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
IPR018234. GTP_CycHdrlase_I_CS.
[Graphical view]
KOK01495.
PANTHERPTHR11109. GTP_cyclohydro_I. 1 hit.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
TIGRFAMsTIGR00063. FolE. 1 hit.
PROSITEPS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
PS00860. GTP_CYCLOHYDROL_1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5V3T4_SPHWW
AccessionPrimary (citable) accession number: A5V3T4
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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