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A5V202

- A5V202_ROSS1

UniProt

A5V202 - A5V202_ROSS1

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Protein

Histidine--tRNA ligase

Gene

hisS

Organism
Roseiflexus sp. (strain RS-1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His).UniRule annotationSAAS annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. histidine-tRNA ligase activity Source: UniProtKB-EC

GO - Biological processi

  1. histidine biosynthetic process Source: InterPro
  2. histidyl-tRNA aminoacylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetaseUniRule annotationSAAS annotation, Ligase

Keywords - Biological processi

Protein biosynthesisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciRSP357808:GH5Z-4628-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Histidine--tRNA ligaseUniRule annotation (EC:6.1.1.21UniRule annotation)
Alternative name(s):
Histidyl-tRNA synthetaseUniRule annotation
Gene namesi
Name:hisSUniRule annotation
Ordered Locus Names:RoseRS_4574Imported
OrganismiRoseiflexus sp. (strain RS-1)Imported
Taxonomic identifieri357808 [NCBI]
Taxonomic lineageiBacteriaChloroflexiChloroflexiaChloroflexalesRoseiflexineaeRoseiflexaceaeRoseiflexus
ProteomesiUP000006554: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi357808.RoseRS_4574.

Structurei

3D structure databases

ProteinModelPortaliA5V202.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-II aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0124.
HOGENOMiHOG000018071.
KOiK01892.
OMAiIFSITKA.
OrthoDBiEOG6BPDH4.

Family and domain databases

Gene3Di3.40.50.800. 1 hit.
HAMAPiMF_00125. HisZ.
MF_00127. His_tRNA_synth.
InterProiIPR006195. aa-tRNA-synth_II.
IPR004154. Anticodon-bd.
IPR015807. His-tRNA-ligase.
IPR004516. HisRS/HisZ.
IPR004517. HisZ.
[Graphical view]
PANTHERiPTHR11476. PTHR11476. 1 hit.
PfamiPF03129. HGTP_anticodon. 1 hit.
[Graphical view]
PIRSFiPIRSF001549. His-tRNA_synth. 1 hit.
SUPFAMiSSF52954. SSF52954. 1 hit.
TIGRFAMsiTIGR00442. hisS. 1 hit.
PROSITEiPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5V202-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSNRVQNIRG MRDHLPSAMI LRQYIIDTLT SVFERYGFEP LQTPVVEYAE
60 70 80 90 100
TLDGKIGDDE KLIYRFEDHG GRKVALRYDQ TVPLARVVAQ YQGQLLFPWR
110 120 130 140 150
RYAIGQSYRG ERPGRGRYRE LWQADIDIVG SASPLADAEI LAVLTDALTA
160 170 180 190 200
LGFTGFTTLI SHRQILGGIA RVSGLDDAAA GDVYRAIDKL DKIGIDGVRN
210 220 230 240 250
DLLQSGVSTA AAERILALID LQGDADEVLN ALAQQLQGDE RALQAIDNVR
260 270 280 290 300
AIIGYARAMG VPEERIVIAP RLARGLSYYT GAVFESIVQN PPMGSLLGGG
310 320 330 340 350
RYDELIGMFA GRSIPTVGLA FGIERLHDVM EELGMGPASR TIATAFVTLF
360 370 380 390 400
NPDMAAESLR LAQELRRAGL LVETALDPSE KLGKQLQYAD RRGIPYALVI
410 420 430 440 450
GPDELARGEV VVKDLRSGAQ QSVVRSAVAS QLRSAADARR TPRTAYDQGG

THERQTS
Length:457
Mass (Da):49,924
Last modified:July 10, 2007 - v1
Checksum:iDEC88B1F10644C4D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000686 Genomic DNA. Translation: ABQ92905.1.
RefSeqiWP_011959242.1. NC_009523.1.
YP_001278855.1. NC_009523.1.

Genome annotation databases

EnsemblBacteriaiABQ92905; ABQ92905; RoseRS_4574.
GeneIDi5211560.
KEGGirrs:RoseRS_4574.
PATRICi23358068. VBIRosSp109359_5060.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000686 Genomic DNA. Translation: ABQ92905.1 .
RefSeqi WP_011959242.1. NC_009523.1.
YP_001278855.1. NC_009523.1.

3D structure databases

ProteinModelPortali A5V202.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 357808.RoseRS_4574.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABQ92905 ; ABQ92905 ; RoseRS_4574 .
GeneIDi 5211560.
KEGGi rrs:RoseRS_4574.
PATRICi 23358068. VBIRosSp109359_5060.

Phylogenomic databases

eggNOGi COG0124.
HOGENOMi HOG000018071.
KOi K01892.
OMAi IFSITKA.
OrthoDBi EOG6BPDH4.

Enzyme and pathway databases

BioCyci RSP357808:GH5Z-4628-MONOMER.

Family and domain databases

Gene3Di 3.40.50.800. 1 hit.
HAMAPi MF_00125. HisZ.
MF_00127. His_tRNA_synth.
InterProi IPR006195. aa-tRNA-synth_II.
IPR004154. Anticodon-bd.
IPR015807. His-tRNA-ligase.
IPR004516. HisRS/HisZ.
IPR004517. HisZ.
[Graphical view ]
PANTHERi PTHR11476. PTHR11476. 1 hit.
Pfami PF03129. HGTP_anticodon. 1 hit.
[Graphical view ]
PIRSFi PIRSF001549. His-tRNA_synth. 1 hit.
SUPFAMi SSF52954. SSF52954. 1 hit.
TIGRFAMsi TIGR00442. hisS. 1 hit.
PROSITEi PS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RS-1Imported.

Entry informationi

Entry nameiA5V202_ROSS1
AccessioniPrimary (citable) accession number: A5V202
Entry historyi
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: October 29, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3