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A5V0B3 (RNPA_ROSS1) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease P protein component

Short name=RNase P protein
Short name=RNaseP protein
EC=3.1.26.5
Alternative name(s):
Protein C5
Gene names
Name:rnpA
Ordered Locus Names:RoseRS_3966
OrganismRoseiflexus sp. (strain RS-1) [Complete proteome] [HAMAP]
Taxonomic identifier357808 [NCBI]
Taxonomic lineageBacteriaChloroflexiChloroflexalesChloroflexaceaeRoseiflexus

Protein attributes

Sequence length122 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme By similarity. HAMAP-Rule MF_00227

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00227

Subunit structure

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit By similarity.

Sequence similarities

Belongs to the RnpA family.

Ontologies

Keywords
   Biological processtRNA processing
   LigandRNA-binding
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionribonuclease P activity

Inferred from electronic annotation. Source: UniProtKB-EC

tRNA binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 122122Ribonuclease P protein component HAMAP-Rule MF_00227
PRO_1000021453

Sequences

Sequence LengthMass (Da)Tools
A5V0B3 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 367EF94D0C4433CA

FASTA12213,916
        10         20         30         40         50         60 
MKRAYRLRTP EQYQRVRRDG RTWDAGMLML NAAPNRRRLS RCGFVTPKRL GGAVTRNRIR 

        70         80         90        100        110        120 
RRVREAVRLL YPQIVPGWDI VFIARSPALA EIAFPQLQAL VQQALQRAGV LQASDSGQSD 


MG 

« Hide

References

[1]"Complete sequence of Roseiflexus sp. RS-1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Bryant D.A., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RS-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000686 Genomic DNA. Translation: ABQ92316.1.
RefSeqYP_001278266.1. NC_009523.1.

3D structure databases

ProteinModelPortalA5V0B3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING357808.RoseRS_3966.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABQ92316; ABQ92316; RoseRS_3966.
GeneID5210950.
KEGGrrs:RoseRS_3966.
PATRIC23356745. VBIRosSp109359_4403.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGNOG126212.
HOGENOMHOG000266301.
KOK03536.
OMAGWDIVFI.
OrthoDBEOG6KT2TP.

Enzyme and pathway databases

BioCycRSP357808:GH5Z-4017-MONOMER.

Family and domain databases

Gene3D3.30.230.10. 1 hit.
HAMAPMF_00227. RNase_P.
InterProIPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
IPR020539. RNase_P_CS.
[Graphical view]
PfamPF00825. Ribonuclease_P. 1 hit.
[Graphical view]
ProDomPD003629. Ribonuclease_P. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF54211. SSF54211. 1 hit.
TIGRFAMsTIGR00188. rnpA. 1 hit.
PROSITEPS00648. RIBONUCLEASE_P. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNPA_ROSS1
AccessionPrimary (citable) accession number: A5V0B3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 10, 2007
Last modified: May 14, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families