A5UY74 (A5UY74_ROSS1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Deoxyribose-phosphate aldolase 2 HAMAP MF_00114
Short name=DERA 2 HAMAP MF_00114
EC=4.1.2.4 HAMAP MF_00114

Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase 2 HAMAP MF_00114
Phosphodeoxyriboaldolase 2 HAMAP MF_00114

Gene names

Name:	deoC2 HAMAP MF_00114
Ordered Locus Names:	RoseRS_3216

Organism

Roseiflexus sp. (strain RS-1) [Complete proteome] [HAMAP] EMBL ABQ91577.1

Taxonomic identifier

357808 [NCBI]

Taxonomic lineage

Bacteria › Chloroflexi › Chloroflexales › Chloroflexaceae › Roseiflexus

Protein attributes

Sequence length	220 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP MF_00114 SAAS SAAS022979
Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114 SAAS SAAS022979
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114 SAAS SAAS022979
Subcellular location	Cytoplasm By similarity HAMAP MF_00114 SAAS SAAS022979.
Sequence similarities	Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. HAMAP MF_00114

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00114 SAAS SAAS022979
Ligand	Schiff base HAMAP MF_00114 SAAS SAAS022979
Molecular function	Lyase SAAS SAAS022979 HAMAP MF_00114 EMBL ABQ91577.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	153	1	Schiff-base intermediate with acetaldehyde By similarity HAMAP MF_00114
	Active site	182	1	By similarity HAMAP MF_00114

Sequences

	Sequence		Length	Mass (Da)
	A5UY74 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: 65F2A84DE50628D7	FASTA	220	22,752
	10 20 30 40 50 60 MNIARMIDHT LLKPDATPQQ IAQICAEARE YGFAAVCVNP VHVAQAAALL LGSATVVCSV 70 80 90 100 110 120 AGFPLGATST AVKVFETRQA IADGAREIDM VISIGHLKHG DNDHVLNDIR SVVEAAHTGG 130 140 150 160 170 180 AICKVIIETA LLTDEEKRRA CILAVEAGAD FVKTSTGFAS GGATVEDVAL MRAVVGNRAR 190 200 210 220 IKAAGGIRTL ADAHAMIAAG AARIGTSSGV AIVRETMDQK

References

[1]

"Complete sequence of Roseiflexus sp. RS-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Bryant D.A., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RS-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000686 Genomic DNA. Translation: ABQ91577.1.
RefSeq	YP_001277527.1. NC_009523.1.
3D structure databases
ProteinModelPortal	A5UY74.
SMR	A5UY74. Positions 2-218.
ModBase	Search...
Protein-protein interaction databases
STRING	A5UY74.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5210188.
GenomeReviews	Gene locus RoseRS_3216 in contig CP000686_GR.
KEGG	rrs:RoseRS_3216.
PATRIC	23355045. VBIRosSp109359_3565.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0274.
HOGENOM	HBG636421.
OMA	IDHTNLK.
ProtClustDB	PRK00507.
Enzyme and pathway databases
BioCyc	RSP357808:ROSERS_3216-MONOMER.
Family and domain databases
HAMAP	MF_00114. DeoC_type1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. IPR022979. Deoxyribose_phosphate_aldo_1. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01619.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. DeoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5UY74_ROSS1

Accession

Primary (citable) accession number: A5UY74

Entry history

Integrated into UniProtKB/TrEMBL:	July 10, 2007
Last sequence update:	July 10, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)