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A5UY58 (A5UY58_ROSS1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha 2 HAMAP MF_00823
Short name=ACCase subunit alpha 2 HAMAP MF_00823
Short name=Acetyl-CoA carboxylase carboxyltransferase subunit alpha 2 HAMAP MF_00823
EC=6.4.1.2 HAMAP MF_00823
Gene names
Name:accA2 HAMAP MF_00823
Ordered Locus Names:RoseRS_3200
OrganismRoseiflexus sp. (strain RS-1) [Complete proteome] [HAMAP] EMBL ABQ91561.1
Taxonomic identifier357808 [NCBI]
Taxonomic lineageBacteria › Chloroflexi › Chloroflexales › Chloroflexaceae › Roseiflexus

Protein attributes

Sequence length278 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA By similarity. HAMAP MF_00823

Catalytic activity

ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA. HAMAP MF_00823

Pathway

Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1. HAMAP MF_00823

Subunit structure

Acetyl-CoA carboxylase is an heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD) By similarity. HAMAP MF_00823

Subcellular location

Cytoplasm By similarity HAMAP MF_00823.

Sequence similarities

Belongs to the AccA family. HAMAP MF_00823

Sequences

Sequence LengthMass (Da)Tools
A5UY58 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: A8870070808A8524

FASTA27830,511
        10         20         30         40         50         60 
MTQTLTPWDK VQLARHMQRP RTLDYIRGLC DDFVELHGDR RFGDDAAIVG GVATFEGRTV 

        70         80         90        100        110        120 
VLVGHQKGRD ARENIRRNFG MPHPEGYRKA LRLFQHAEKF GFPVICFIDT PGANPNRESE 

       130        140        150        160        170        180 
ERGQANAIAE NILTMAGLKT PIIACVIGEG GSGGALAIGV ADRILMLEHA IYSVASPEAA 

       190        200        210        220        230        240 
ASIIWRDAAK APDAARAMRI TAQDLLELGI IDEIVPEPSG GAHADPTTMV ATLGDAIRRH 

       250        260        270 
LNQLLAFDIE TLLQHRYERY RAIGRYEEDA SGILHTVN

« Hide

References

[1]"Complete sequence of Roseiflexus sp. RS-1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Bryant D.A., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RS-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000686 Genomic DNA. Translation: ABQ91561.1.
RefSeqYP_001277511.1. NC_009523.1.

3D structure databases

ProteinModelPortalA5UY58.
SMRA5UY58. Positions 3-265.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5UY58.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5210171.
GenomeReviewsGene locus RoseRS_3200 in contig CP000686_GR.
KEGGrrs:RoseRS_3200.
PATRIC23355009. VBIRosSp109359_3548.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0825.
HOGENOMHBG286557.
OMAFHRPIVT.
ProtClustDBCLSK972928.

Enzyme and pathway databases

BioCycRSP357808:ROSERS_3200-MONOMER.

Family and domain databases

HAMAPMF_00823. AcetylCoA_CT_alpha.
[Tree]
InterProIPR001095. Acetyl_CoA_COase_a_su.
IPR011763. COA_CT_C.
[Graphical view]
KOK01962.
PANTHERPTHR22855:SF3. Ac-CoA_carboxylA. 1 hit.
PfamPF03255. ACCA. 1 hit.
[Graphical view]
PRINTSPR01069. ACCCTRFRASEA.
TIGRFAMsTIGR00513. AccA. 1 hit.
PROSITEPS50989. COA_CT_CTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5UY58_ROSS1
AccessionPrimary (citable) accession number: A5UY58
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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