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Protein

Glutamyl-tRNA(Gln) amidotransferase subunit A

Gene

gatA

Organism
Roseiflexus sp. (strain RS-1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).UniRule annotation

Catalytic activityi

ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei79Charge relay systemUniRule annotation1
Active sitei154Charge relay systemUniRule annotation1
Active sitei178Acyl-ester intermediateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciRSP357808:G1G8U-3077-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamyl-tRNA(Gln) amidotransferase subunit AUniRule annotation (EC:6.3.5.7UniRule annotation)
Short name:
Glu-ADT subunit AUniRule annotation
Gene namesi
Name:gatAUniRule annotation
Ordered Locus Names:RoseRS_2947
OrganismiRoseiflexus sp. (strain RS-1)
Taxonomic identifieri357808 [NCBI]
Taxonomic lineageiBacteriaChloroflexiChloroflexiaChloroflexalesRoseiflexineaeRoseiflexaceaeRoseiflexus
Proteomesi
  • UP000006554 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002030451 – 487Glutamyl-tRNA(Gln) amidotransferase subunit AAdd BLAST487

Interactioni

Subunit structurei

Heterotrimer of A, B and C subunits.UniRule annotation

Protein-protein interaction databases

STRINGi357808.RoseRS_2947

Structurei

3D structure databases

ProteinModelPortaliA5UXF9
SMRiA5UXF9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the amidase family. GatA subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C3P Bacteria
COG0154 LUCA
HOGENOMiHOG000116697
KOiK02433
OMAiPITQNVE
OrthoDBiPOG091H00O9

Family and domain databases

Gene3Di3.90.1300.101 hit
HAMAPiMF_00120 GatA, 1 hit
InterProiView protein in InterPro
IPR000120 Amidase
IPR020556 Amidase_CS
IPR023631 Amidase_dom
IPR036928 AS_sf
IPR004412 GatA
PANTHERiPTHR11895 PTHR11895, 1 hit
PfamiView protein in Pfam
PF01425 Amidase, 1 hit
SUPFAMiSSF75304 SSF75304, 1 hit
TIGRFAMsiTIGR00132 gatA, 1 hit
PROSITEiView protein in PROSITE
PS00571 AMIDASES, 1 hit

Sequencei

Sequence statusi: Complete.

A5UXF9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLLHQLTLS DAREALMRGE ITSVELTDAL LARIAAVEPQ VRAFLTIDAE
60 70 80 90 100
GARAQAQAAD ARRAAGDTSP LLGIPLGIKD VISTQGVRTT CASKMLENYV
110 120 130 140 150
PVYDATAVAR LKAAGAVLIG KLNCDEFAMG SSTENSAFQQ TRNPWNLERV
160 170 180 190 200
PGGSSGGSAA AVAAGEAPAT LGTDTGGSIR QPAALCGITG LKPTYGRVSR
210 220 230 240 250
YGLVAFASSL DQIGPMARTV RDCAIILRVI AGADPFDATC TDHPVPDYEA
260 270 280 290 300
ALTGDIRGLR IGVPREYFVA GMQPEVESAV RVAIDVLRDQ GAEVREISLP
310 320 330 340 350
HTPYALPVYY LIAPAEASAN LARFDGVRYG LRVPGESYFD ELERTRGAGF
360 370 380 390 400
GPEVRRRIML GTYALSAGYY DAYYKRAQQV RTLIRRDYQQ AFEQVDVIAA
410 420 430 440 450
PTTPTVAFPI GAHSDDPLAM YLEDVCTLPL NLAGLPGLVV PCGFAAGLPI
460 470 480
GLQLIGRAFD EETLLRIGDA YQRVTDWHTR MPDLPVE
Length:487
Mass (Da):52,086
Last modified:July 10, 2007 - v1
Checksum:iFA90090D7CCD39DF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000686 Genomic DNA Translation: ABQ91312.1
RefSeqiWP_011957656.1, NC_009523.1

Genome annotation databases

EnsemblBacteriaiABQ91312; ABQ91312; RoseRS_2947
KEGGirrs:RoseRS_2947

Similar proteinsi

Entry informationi

Entry nameiGATA_ROSS1
AccessioniPrimary (citable) accession number: A5UXF9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 10, 2007
Last modified: February 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome