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Protein

6-phosphofructokinase

Gene

RoseRS_2734

Organism
Roseiflexus sp. (strain RS-1)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.SAAS annotation

Catalytic activityi

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate.SAAS annotation

Cofactori

Mg2+SAAS annotation

Pathwayi: glycolysis

This protein is involved in step 3 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.SAAS annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. 6-phosphofructokinase (RoseRS_1831), ATP-dependent 6-phosphofructokinase (pfkA), 6-phosphofructokinase (RoseRS_2734)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseSAAS annotationImported, Transferase
Biological processGlycolysisSAAS annotation
LigandATP-bindingSAAS annotation, MagnesiumSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciRSP357808:G1G8U-2856-MONOMER
UniPathwayiUPA00109; UER00182

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphofructokinaseSAAS annotation (EC:2.7.1.11SAAS annotation)
Gene namesi
Ordered Locus Names:RoseRS_2734Imported
OrganismiRoseiflexus sp. (strain RS-1)Imported
Taxonomic identifieri357808 [NCBI]
Taxonomic lineageiBacteriaChloroflexiChloroflexiaChloroflexalesRoseiflexineaeRoseiflexaceaeRoseiflexus
Proteomesi
  • UP000006554 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi357808.RoseRS_2734

Structurei

3D structure databases

ProteinModelPortaliA5UWV3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 311PFKInterPro annotationAdd BLAST305
Domaini391 – 675PFKInterPro annotationAdd BLAST285

Phylogenomic databases

eggNOGiENOG4107S9E Bacteria
COG0205 LUCA
HOGENOMiHOG000200154
KOiK00850
OMAiKQYDELC
OrthoDBiPOG091H01AC

Family and domain databases

InterProiView protein in InterPro
IPR009161 6-Pfructokinase_euk
IPR022953 ATP_PFK
IPR015912 Phosphofructokinase_CS
IPR000023 Phosphofructokinase_dom
IPR035966 PKF_sf
PfamiView protein in Pfam
PF00365 PFK, 2 hits
PIRSFiPIRSF000533 ATP_PFK_euk, 1 hit
PRINTSiPR00476 PHFRCTKINASE
SUPFAMiSSF53784 SSF53784, 2 hits
TIGRFAMsiTIGR02478 6PF1K_euk, 1 hit
PROSITEiView protein in PROSITE
PS00433 PHOSPHOFRUCTOKINASE, 2 hits

Sequencei

Sequence statusi: Complete.

A5UWV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRSTGIGVL TSGGDAPGMN AALRAVVRTA LSRSVPVYAI YEGYRGMVEG
60 70 80 90 100
GDRIRPLGWD DVGGIMHRGG TIIGTARCRE FRTREGRLQA AANLIAHGIN
110 120 130 140 150
RLVVIGGDGS LTGADTFRRE WSSLLAELVE TGKLSRDTAA QYPFLALVGL
160 170 180 190 200
VGSIDNDFYG TDMTIGADSA LHRITAAIDA LVSTAASHQR TFVVEVMGRH
210 220 230 240 250
CGYLALMGAI AGGADYVLIP ENPPEPGWED RMCTLLRAGR ASGRRESIVV
260 270 280 290 300
IAEGARDRDG NPISADYVRR VLEERMGEDA RVTILGHVQR GGTPSAFDRW
310 320 330 340 350
MSTLVGYAAV EELLSATPER EPQLIGMRYH RITRQPLMHC VEQTRQVATA
360 370 380 390 400
INAGDYQRAM ELRSGSFKEM FQTFQALSSA LPSVTRARKS RIALLHAGGP
410 420 430 440 450
APGMNTAIRA AVRLGLDQGH TMLVVRNGFD GLIAGEISEC EWQTVDGWGA
460 470 480 490 500
MGGAELGTSR RVPAGEDLAA VAQALTRHRI DGLLVIGGWN GYQAAHRLYQ
510 520 530 540 550
ERAAYESFNI PIICLPASIN NDLPGSELSI GADTALNAIV ESLDRIKQSA
560 570 580 590 600
VAVRRTFVVE VMGRYCGYLA LMSGLASGAE RVYLHEEGIT LDDLRTDIQM
610 620 630 640 650
MIEGFRHGKR LSLIIRNEYA NRLYTTDVIC ALFEEEGKDL FDVRRAVLGH
660 670 680 690 700
LQQGGSPSPY DRIQATRLAA RCIRFLSEEL DRGTAAAAFI GFVNGKVRVF
710 720 730 740
DLGELPHMVD AAFRRPKDQW WLELAPIARA LAQQKYDTRE A
Length:741
Mass (Da):80,754
Last modified:July 10, 2007 - v1
Checksum:i7AE80DC78D53C6D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000686 Genomic DNA Translation: ABQ91106.1
RefSeqiWP_011957450.1, NC_009523.1

Genome annotation databases

EnsemblBacteriaiABQ91106; ABQ91106; RoseRS_2734
KEGGirrs:RoseRS_2734

Similar proteinsi

Entry informationi

Entry nameiA5UWV3_ROSS1
AccessioniPrimary (citable) accession number: A5UWV3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: March 28, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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