Skip Header

Contribute Send feedback
Read comments (?) or add your own

A5UUJ1 (A5UUJ1_ROSS1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Aerobic magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase HAMAP MF_01840
Short name=Aerobic Mg-protoporphyrin IX monomethyl ester oxidative cyclase HAMAP MF_01840
EC=1.14.13.81 HAMAP MF_01840
Gene names
Name:acsF HAMAP MF_01840
Ordered Locus Names:RoseRS_1905
OrganismRoseiflexus sp. (strain RS-1) [Complete proteome] [HAMAP] EMBL ABQ90294.1
Taxonomic identifier357808 [NCBI]
Taxonomic lineageBacteria › Chloroflexi › Chloroflexales › Chloroflexaceae › Roseiflexus

Protein attributes

Sequence length371 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) By similarity. HAMAP MF_01840

Catalytic activity

131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O. HAMAP MF_01840

131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = divinylprotochlorophyllide + NADP+ + 2 H2O. HAMAP MF_01840

Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O. HAMAP MF_01840

Cofactor

Iron By similarity. HAMAP MF_01840

Pathway

Porphyrin biosynthesis; bacteriochlorophyll biosynthesis (light-independent). HAMAP MF_01840

Sequence similarities

Belongs to the AcsF family. HAMAP MF_01840

Sequences

Sequence LengthMass (Da)Tools
A5UUJ1 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 01324893EDC8404F

FASTA37143,792
        10         20         30         40         50         60 
MMNIPGEYTP TTRHALREAI LNPRFYTTDF RAIDRLNVAH MRDEFDWIRN EFEVDYNRKH 

        70         80         90        100        110        120 
FVRNDEFLAN FDDMPARDLF IEFLERSCTA EFSGCLLYAE MVKHLHDPTL KAIFRCMSRD 

       130        140        150        160        170        180 
EGRHAGFLNK TMADLGVEMN LQVLHTRKKY TYFQPKFIFY SVYLSEKIGY ARYITIYRHL 

       190        200        210        220        230        240 
QKYPQGMIHP IFKWFEKWCN DEYRHGEFFS LLMRSQPDLL RGGNLRWIRF FLLAVYATMY 

       250        260        270        280        290        300 
LNDARRAGFY QALGLDWRDY DQRVIRLTNH IATQVFPVTL PVDDPRFFRH LDACVTYDAQ 

       310        320        330        340        350        360 
IRALEGRSDP IATAQRARLG AAIAARLLAT YRLPVVPTTD ANRWQGLEGF PNYPGPGWKQ 

       370 
DATLNQRVIS A

« Hide

References

[1]"Complete sequence of Roseiflexus sp. RS-1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Bryant D.A., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RS-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000686 Genomic DNA. Translation: ABQ90294.1.
RefSeqYP_001276244.1. NC_009523.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA5UUJ1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5208866.
GenomeReviewsGene locus RoseRS_1905 in contig CP000686_GR.
KEGGrrs:RoseRS_1905.
PATRIC23352096. VBIRosSp109359_2101.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGNOG10633.
HOGENOMHBG284843.
OMAHGDFFDA.
ProtClustDBPRK13654.

Enzyme and pathway databases

BioCycRSP357808:ROSERS_1905-MONOMER.

Family and domain databases

HAMAPMF_01840. AcsF.
[Tree]
InterProIPR008434. AcsF.
IPR012347. Ferritin-rel.
IPR009078. Ferritin/RR-like.
IPR003251. Rubrerythrin.
[Graphical view]
Gene3DG3DSA:1.20.1260.10. Ferritin_rel. 1 hit.
KOK04035.
PfamPF02915. Rubrerythrin. 1 hit.
[Graphical view]
SUPFAMSSF47240. Ferritin/RR_like. 1 hit.
TIGRFAMsTIGR02029. AcsF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA5UUJ1_ROSS1
AccessionPrimary (citable) accession number: A5UUJ1
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info